Ube Industries, Inc.

Chugai Seiyaku Kabushiki Kaisha

Sankyo Company, Limited

The University of Tokyo

Kikuo Ataka

Hiroyuki Miyata

Yasuhito Yamamoto

Naoyuki Yokota

Akira Takama

Kenji Hirotsu

Fumio Toda

Takashi Honma

Kiyotaka Yoshii

Koichi Tanaka

Tetsurou Tsuji

Masayoshi Oku

Yasuhiro Yoneda

Koji Imaoka

Masahiko Kohno

Tatsuya Kawaguchi

Nobuya Satake

Masahiko Hagihara

Kenji Fukunaga

Junichi Yoshida

Yasushi Yamamoto

Noboru Kakeya

Kazuhiro Mae

Shinichiro Uchiumi

Hiroshi Shiraishi

Fumio Iwata

Hisashi Ohsaki

Osamu Fujimura

Tetsuro Tsuji

Hirotaka Kawamura

Norio Ohtsu

Naotaka Hamasaki

Kazuma Sakata

Kiyosi Oomori

Jun Haruta

Akihiro Matsubayashi

Sumio Umumura

Ichiro Nakakoshi

Masahiko Kouno

Hiroyuki Suenaga

Kiyoshi Omori

A terminally-modified polybranched polyimide which can be efficiently complexed with an inorganic material is obtained by reacting a component (a): tetracarboxylic dianhydride; a component (b): as an amine component, a mixture of a triamine and a diamine (which may be composed of a triamine only); and a component (c): as a terminal component, a compound selected from general formulae (1-1) to (1-4).HN&#x2014;X&#x2014;R&#x2003;&#x2003;(1-1)  

Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same

An aligned metal-particle film, in which metal particles are aligned in a polymer as a layer with a certain interval in parallel with a substrate is disclosed. The aligned metal-particle film is manufactured by forming a polymer film containing a metal component on a reflecting substrate; and irradiating the polymer film with light at a particular wavelength, whereby metal particles are aligned in parallel with the substrate in the polymer.

Optical multilayer reflective film, and aligned metal particle film and manufacturing process therefor

The method for producing an aldehyde or ketone compound from a corresponding primary or secondary alcohol at relatively high temperature within a short time with a high yield including a step (1) of reacting a sulfoxide compound with an activating agent to produce an activation reaction product; a step (2) of reacting the activation reaction product with a primary or secondary alcohol to produce an alkoxysulfonium salt; and a step (3) of reacting the reaction product with a base to produce an aldehyde or ketone; wherein at least one of the steps, preferably the step (1) and step (2), are carried out by using a microreactor.

Method for producing aldehyde compound or ketone compound by using microreactor

The present invention is to provide a process for producing a 2'-O-acetyl-4&#x2033;-formyl-8,9-anhydroerythromycin A 6,9-hemiketal compound 4, and it provide a process for producing an erythromycin compound which comprises reacting a formylating agent with a 2&#x2032;-O-acetylerythromycin A compound 2 to obtain 2-&#x2032;-O-acetyl-4&#x2033;-O-formylerythromycin A compound 3, then, acting an acid on Compound 3 to subject to hemiketalation, and then adding an aqueous basic solution in an aqueous solution to precipitate Compound 4 as free crystals.

Process for preparing erythromycin compound

A production process, especially a continuous production process, for a biphenyltetracarboxylic acid tetraester characterized by carrying out, in parallel, a step of preliminarily mixing a phthalic acid diester and a palladium compound-containing catalyst to prepare a starting mixture, a step of continuously or intermittently supplying the starting mixture to a reactor, a step of conducting oxidative dimerization reaction of the phthalic acid diester in a temperature range of from 140&#xb0; C. and lower than 250&#xb0; C. while supplying molecular oxygen to the reactor to form a reaction mixture in the reactor, and a step of continuously or intermittently removing a portion of the reaction mixture from the reactor. Preferably, the palladium compound-containing catalyst in the starting mixture is dissolved in the phthalic acid diester, the palladium compound-containing catalyst comprises a palladium compound, a bidentate ligand and a copper compound, the reactor consists of a plurality of serially connected reactors and a carboxylic acid is also continuously or intermittently supplied to the reactor.

Process for production of biphenyltetracarboxylic acid tetraesters

The present invention is to provide a process for producing a 2'-O-acetyl-4&#x2033;-O-formyl-8,9-anhydroerythromycin A 6,9-hemiketal compound, and it provide a process for producing an erythromycin compound which comprises reacting a formylating agent with a 2&#x2032;-O-acetylerythromycin A compoundto obtain 2&#x2032;-O-acetyl-4&#x2033;-O-formylerythromycin A compound, then, acting an acid on Compoundto subject to hemiketalation, and then adding an aqueous basic solution in an aqueous solution to precipitate Compoundas free crystals.

Process for preparation of erythromycin compounds

7a-alkoxy-4H-pyrano&lsqb;3,2-d&rsqb;-oxazol-2(3H)-one and process for producing the same

Process for producing 4-alkoxycarbonyl-2-oxazolidinone compound

The present invention is to provided a trifluoro-substituted benzoic acid, an ester thereof, particularly 2,3,4-trifluoro-5-iodobenzonic acid, 2,3,4-trifluoro-5-trifluoromethylbenzonic acid, esters thereof, which are useful as a starting material for synthesizeing a quinolonecarboxylic acid compound useful as a medicine, an anti-bacterial agent or an antiviral agent, and processes for preparing these compounds and 2,4,5-trifluoro-3-iodobenzonic acid, 2,4,5-trifluoro-3-trifluoromethylbenzoic acid and esters thereof.

Trifluoro-substituted benzoic acid, esters thereof and processes for preparing the same

Trifluoro-substituted benzoic acid, esters thereof, and process for

In a process for preparing an optically active .beta.-hydroxyester derivative by enantioselective aldol addition reaction between an aldehyde and a ketene silylacetal, the enantioselective aldol addition reaction is performed in the presence of an organic base and a platinum-containing catalyst composed of an optically active bisphosphine-platinum complex having two P--Pt bondings which are equivalent to each other, showing in its .sup.31 P NMR spectrum a single peak assigned to P--Pt bonding.

Preparation of optically active .beta.-hydroxyester derivatives and

13-membered ring macrolide compound, medicine containing the same, and

5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same

2-silyloxy-tetrahydrothienopyridine, salt thereof and process for

A process of separation and purification of a propargyl alcohol which comprises treating a propargyl alcohol represented by Formula (I): ##STR1## wherein each of R.sub.1 and R.sub.2 represents a substituent which is different from each other, and is selected from the group consisting of a C.sub.1 -C.sub.8 alkyl group, a phenyl group; a halophenyl group, a phenyl group having at least one methyl substituent, an aralkyl group and a cycloalkyl group, which is chemically or optically impure, with a tertiary diamine represented by Formula (II): ##STR2## wherein each of R.sub.3, R.sub.4, R.sub.5 and R.sub.6 may be the same or different and represents an aralkyl group or an alkyl group having 1 to 6 carbon atoms; and R.sub.3, R.sub.4, R.sub.5 and R.sub.6 may be bonded to each other, to form a crystalline complex compound of the propargyl alcohol represented by Formula (I) and the tertiary diamine represented by Formula (II), separating and purifying the resulting compound, and treating the resultant compound with an acid to isolate the propargyl alcohol represented by Formula (I).

Process of separation and purification of a propargyl alcohols

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Ube, Japan

Kikuo Ataka