Daicel Chemical Industries, Ltd.

Sapporo Breweries Limited

Other

Etsuo Ito

Sapparo Breweries Limited

Kiichi Uchida

Kohei Kobayashi

Hisao Kado

Nobuhiro Watanabe

Suguru Takeo

Yoshitada Mori

Takuro Karakawa

Eichi Soma

Shigeyoshi Kato

Minoru Kamimura

Saburo Sone

Hisao Yamamoto

Masanobu Munekata

Kazumaro Seto

Akito Nakamura

Lymphokine activated killer suppressive factor (LAKSF) and a process for producing the LAKSF by cultivating human mono-cytic cells for alveolar macrophages activated by a stimulator to produce LAKSF and harvesting it. The LAKSF has a LAK induction suppressive activity and an immunosuppressive effect and thus the LAKSF is useful as a medicine.

Lymphokine activated killer suppressive factor (LAKSF), process for

A polysaccharide RDP substance having the ultraviolet absorption spectrum depicted in FIG. 1, the infrared absorption spectrum depicted in FIG. 2 and the .sup.13 C-NMR spectrum depicted in FIG. 3 is obtained from rice bran by extraction.

Polysaccharide RDP substance

A polysaccharide RON substance having the ultraviolet absorption spectrum depicted in FIG. 1, the infrared absorption spectrum depicted in FIG. 2 and the .sup.13 C-NMR spectrum depicted in FIG. 3 is obtained from rice bran by extraction and purification; and pharmacological composition containing said RON substance.

Polysaccharide RON substance

Polysaccharide RBS substance is obtained from rice bran by extraction it with hot water. RBS substance is utilized for antitumor agent.

Process for the production of polysaccharide RBS substance

A polysaccharide RBS substance having the ultraviolet absorption spectrum depicted in FIG. 1 and the infrared absorption spectrum depicited in FIG. 2 is obtained from rice bran by extraction with hot water. These substances have been tested for anti-tumor activity against Sarcoma 180 ascites tumor and against Ehrlich ascites tumor and were determined to have anti-tumor activity against these tested tumors.

Polysaccharide RBS substance and antitumor agent containing same

Growing community of inventors

Fujisawa, Japan

Kiichi Uchida