Yield10 Bioscience, Inc.

Kieran Ryan

Oliver P Peoples

Frank Anthony Skraly

Kristi D Snell

Meghna Malik

Jihong Tang

Madana M R Ambavaram

Nirmala Sharma

Venkatesh Bollina

Yuanyuan Ji

Claire Burkitt

A genetically engineered land plant that expresses a protein that has homology to a plant invertase inhibitor and/or a pectin methylesterase inhibitor and that increases seed yield with increased expression ('an ISY protein') is disclosed. The plant comprises a modified gene for the ISY protein. The ISY protein comprises one or more of an ISY protein ofcomprising SEQ ID NO: 2 or a fragment,homolog, or ortholog thereof. The modified gene comprises a promoter and a nucleic acid sequence encoding the ISY protein. The promoter is non-cognate with respect to the nucleic acid sequence encoding the ISY protein. The modified gene is configured such that transcription of the nucleic acid sequence is initiated from the promoter and results in expression of the ISY protein. A genetically engineered land plant that expresses an RNA that increases seed yield with increased expression also is disclosed.

Genetically engineered land plants that express an increased seed yield protein and/or an increased seed yield RNA

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Sharon, MA, United States of America

Kieran Ryan