Postech Academy-industry Foundation

Lg Electronics Inc.

Seoul National University

Postech Research and Business Development Foundation

Yonsei University

University of Ulsan Foundation for Industry Cooperation

The Asan Foundation

Osong Medical Innovation Foundation

Postech Academy Foundation

Ki Hean Kim

Jung Hoon Lee

Hoon Jang

Kwang Heum Baik

Dokyoung Kim

Kyo Han Ahn

Myoung Joon Kim

Seonghan Kim

Viet Hoan Le

Seong Han Kim

Seunghun Lee

Chang Ho Yoon

Jun Ho Lee

Hak Su Kim

Won Kyu Ha

Jae Do Lee

Sungjee Kim

Hyun Joung Kim

Seong Hun Lee

Jung Min Seo

Do Young Kum

Seung Jae Myung

Soohyun Park

Hye Gun Ryu

Jungbin Lee

Bumju Kim

Jung Bin Lee

Soo Hyun Park

Do Young Rum

Sejung Yang

Hyunsoo Moon

Kyungbin Bae

Seungrag Lee

Wonyeong Park

Jin Hyoung Park

Bum Ju Kim

Tae Jun Wang

Provided is a photographing apparatus including an image capturing unit including a first light source, an object lens, and a first light detector, a surface detecting unit including a second light source, the object lens, and a second light detector, a processor configured to obtain a strong reflection signal area where a reflection signal is strong in an oblique plane image obtained from the second light detector, and obtain a relative position relationship between a region of interest and a focal plane of the object lens, and an actuator configured to adjust the region of interest to be in focus.

Photographing apparatus and photographing method

An apparatus for imaging examination of cells on a surface of living tissue using moxifloxacin. includes: a light source emitting light towards living tissue stained with moxifloxacin; a photographing unit photographing the living tissue subjected to fluorescence excitation by the light emitted from the light source; a lens unit controlling the light emitted from the light source or a fluorescence path of moxifloxacin excited by the light; an objective lens controlling a focus of the photographing unit; an active lens disposed between the objective lens and the photographing unit and changing a focal position on the living tissue; and an image generator performing image processing of a cell image of the living tissue photographed by the photographing unit to generate an in-focus image, in which the entirety of the cell image is in focus.

Apparatus and method for imaging examination of cells on surface of living tissue using moxifloxacin

A fluorescence endoscopic method for visualization of colorectal tissue using a fluoroquinolone antibiotic and a method for diagnosis of lesions of colorectal tissue using the same. The fluorescence endoscopic method for visualization of colorectal tissue includes staining goblet cells of the colorectal tissue with moxifloxacin, which is a fluoroquinolone antibiotic, and exciting the stained goblet cells with single photons in the near UV region or in the visible region, followed by fluorescence endoscopic photographing of the goblet cells, thereby enabling acquisition of morphological information on living tissue without damage to or destruction of the colorectal tissue, while allowing diagnosis of lesions of the colon based on the morphological information on living tissue such as information on the distribution of the goblet cells. Specifically, the fluorescence endoscopic method includes: a colorectal tissue staining step in which the crypt of the colorectal tissue is stained with a fluoroquinolone antibiotic; an image pickup unit insertion step in which an image pickup unit is inserted into the colon; a light irradiation step in which the colorectal tissue is irradiated with excitation light from a light source of the image pickup unit; a colorectal tissue photographing step in which the colorectal tissue is photographed using a photographing device of the image pickup unit through the fluoroquinolone antibiotic fluorescence-excited by light in the light irradiation step, wherein, in the colorectal tissue staining step, goblet cells of the crypt are stained with the fluoroquinolone antibiotic; in the light irradiation step, the light source emits single photons as excitation light inducing fluorescence of the fluoroquinolone antibiotic, the excitation light from the light source having a wavelength band within the near UV and visible regions; and, in the image pickup unit insertion step, the image pickup unit is a general fluorescence endoscope or a confocal endoscopic microscope.

Fluorescence endoscopic method for visualization of colorectal tissue using fluoroquinolone antibiotics and method for diagnosis of lesions of colorectal tissue using

A method for visualization of conjunctival cells using fluoroquinolone antibiotics and a method for diagnosis of ocular lesions using the same. The method for visualization of conjunctival cells using fluoroquinolone antibiotics includes staining goblet cells of ocular conjunctiva with moxifloxacin, which is a fluoroquinolone antibiotic, and exciting the stained goblet cells with single photons in the near-UV region or in the visible region, followed by fluorescence photographing of the goblet cells, thereby enabling acquisition of morphological information on living tissue without damage to or destruction of the ocular conjunctiva. Specifically, the method for visualization of conjunctival cells includes: a conjunctiva staining step in which ocular conjunctiva is stained with a fluoroquinolone antibiotic; a light irradiation step in which the ocular conjunctiva stained with the fluoroquinolone antibiotic is irradiated with light from a light source; and a conjunctiva photographing step in which the ocular conjunctiva is photographed using an image pickup unit through the fluoroquinolone antibiotic fluorescence-excited by light in the light irradiation step, wherein, in the conjunctiva staining step, goblet cells of the ocular conjunctiva are stained with the fluoroquinolone antibiotic; in the light irradiation step, the light source emits single photons; and, in the conjunctiva photographing step, the image pickup unit photographing the ocular conjunctiva is a high-magnification fluorescence microscope or a slit lamp microscope.

Method for visualization of conjunctival cells using fluoroquinolone antibiotics and method for diagnosis of ocular lesions using the same

A fluorescent probe for detecting a tyrosine kinase using a compound having an ortho-hydroxy-benzaldehyde structure, and use thereof are provided. The fluorescent probe can show a change in fluorescence when the compound binds with a tyrosine kinase. The compound can be readily synthesized and has high stability and low cytotoxicity in vivo. The fluorescent probe can be used to image cells or tissues overexpressing the tyrosine kinase, the fluorescent probe can be effectively used in a composition for imaging the tissues and a method of imaging the tissues. Also, the fluorescent probe can be used to image cancer cells or tissues since the fluorescent probe can exhibit fluorescence when the fluorescent probe binds to the cancer cells or tissues overexpressing the tyrosine kinase.

Fluorescent probe sensing tyrosine kinase and use thereof

Provided are methods of labeling cells in at least one of a biological tissue, bacteria, and fungi with fluoroquinolone antibiotics (e.g., moxifloxacin and gatifloxacin).

Methods of labeling cells with fluoroquinolone antibiotics

Provided are acedan derivatives having an extended &#x3c0; bond, a method for preparing the acedan derivatives, and a method for two-photon microscopy imaging of amyloid-beta plaque using the acedan derivatives; more particularly, to two-photon absorbing fluorescent compounds having a longer absorption wavelength and emission wavelength than acedan and acedan derivatives which are conventional two-photon absorbing fluorophores. The compounds provided may be usefully used for in vivo imaging studies by imaging cells or tissue using the compounds, and may also be usefully used for diagnosing Alzheimer's disease by imaging amyloid-beta plaque using the compounds.

Pi-extended acedan derivatives, their application for two-photon microscopy imaging, and their application for two-photon microscopy imaging of amyloid-beta plaque in an alzheimer's disease animal model

There is disclosed an electro-luminescence display device that is adaptive for preventing picture quality deterioration by operating a thin film transistor for an electro-luminescence cell drive at a non-saturation area to compensate a threshold voltage, and a driving method thereof. An electro-luminescence display device according to an embodiment of the present invention includes an electro-luminescence cell connected between a first supply voltage source and a ground voltage source to emit light by a current supplied from the first supply voltage source; a cell driver formed every intersection of gate lines and data lines and connected between the first supply voltage source and the electro-luminescence cell to control a current flowing in the pixel cell; and a pulse supplier supplies to the electro-luminescence cell a pulse amplitude modulation signal which is divided to have N (N is a natural number) numbers of different voltage levels from each other, and wherein the driving thin film transistor operates at the non-saturation region.

Electro-luminescence display device and driving method thereof

There are disclosed an organic electro luminescence display device that is adaptive for preventing its light emitting efficiency and picture quality from being deteriorated, and a fabricating method thereof. An organic electro luminescence display device according to an embodiment of the present invention includes an organic electro luminescence array having first and second electrodes formed on a substrate with an organic light emitting layer therebetween, and a barrier rib in parallel to any one of the first and second electrodes; a protective barrier rib formed to be connected to each of the barrier ribs and to enclose the organic electro luminescence array; and at least one dummy barrier rib located at a corner area of the protective barrier rib and connected to the barrier rib and the protective barrier rib.

Organic electro-luminescence display device and fabricating method thereof

There is disclosed an organic electro luminescence display device that is adaptive for preventing the deterioration of its light emitting efficiency and picture quality, and a fabricating method thereof. An organic electro luminescence display device that is adaptive for preventing the deterioration of its light emitting efficiency and picture quality, and a fabricating method thereof are provided. The organic electro luminescence display device as embodied includes an organic electro luminescence array having first and second electrodes formed on a substrate with an organic light emitting layer therebetween, and a barrier rib in parallel to any one of the first and second electrodes; a protective barrier rib formed to enclose the organic electro luminescence array; and at least one dummy barrier rib located inside a corner area of the protective barrier rib and formed to be bent along the protective barrier rib.

Organic electro luminescence display device and fabricating method thereof

Growing community of inventors

Pohang-si, South Korea

Ki Hean Kim