Korea Research Institute of Bioscience and Biotechnology

Khiev Piseth

Kyung Seop Ahn

Jae Wha Kim

Sei Ryang Oh

Ok-Kyoung Kwon

Hee Gu Lee

Ho Bum Kang

Seung Ho Kim

Hyuk Hwan Song

Da Jung Ji

Jang Mi Son

Byeong Hwa Jeon

The present invention relates to a pharmaceutical composition for treating wounds or revitalizing skin comprising theextract, the fractions thereof, or the diterpene compound isolated therefrom as an active ingredient. Theextract may act on epithelial cells to induce PKD1 activity required for improving the reproduction capability of differentiated epithelial cells, and thus may induce the phosphorylation of lower ERK1 and the generation of Cycline D, thus exhibiting an excellent ability to activate the reproduction of damaged skin. Therefore, theextract may be used effectively as an active ingredient in a pharmaceutical composition for treating wounds or reproducing skin, a health food for recovering skin damage or reproducing skin, or a functional cosmetic for inducing skin cell activity.

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Growing community of inventors

Daejeon, South Korea

Khiev Piseth