Omrix Biopharmaceuticals Inc.

Ethicon, Gmbh

Kfir Regev

Erez Ilan

Israel Nur

John Mott Goodman

Dana Leitman

Robert J Tannhauser

Liliana Bar

Moti Meron

Yotam Gurman

John Goodman

Provided are methods and devices for dissolving solid protein compositions, such as solid compositions comprising fibrinogen, in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub-atmospheric. Aqueous solvent is introduced into the container while maintain the sub-atmospheric pressure, and subsequent to addition of the solvent, the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method.

Method and device for fast dissolution of solid protein composition

The presently disclosed subject matter relates to an addition to a medical applicator in general and in particular to an addition to a medical applicator for applying on a surface a curable liquid substance having multi components.

Addition to a medical applicator

The present invention relates to a fibrin matrix, its preparation and use for effectively sealing a defect in a mucosa or other moist tissue.

Method for improved fibrin sealing

Growing community of inventors

Tel Aviv, Israel

Kfir Regev