Genentech, Inc.

F. Hoffmann-la Roche Ag

Keyang Xu

Surinder Kaur

Ola Saad

Jo-Anne Hongo

John B Lowe

Terence Wong

Rajesh Vij

Martine Darwish

Yanhong Li

Luna Liu

Mauricio Maia

Dian Su

Methods to rapidly and accurately detect, characterize, measure, and quantify site-specific antibody drug conjugates, that may be present in pre-clinical animal biological samples, or human biological samples, including plasma/serum and tissue samples.

Bioanalytical analysis of site-specific antibody drug conjugates

The invention provides anti-idiotypic HCMV antibodies as well as methods of using the same.

Idiotypic antibodies and uses thereof

Methods are disclosed to detect, characterize, measure, and quantitate human and humanized antibodies, and their conjugates, present in pre-clinical animal biological samples, including plasma/serum and tissue samples.

Multiple reaction monitoring LC-MS/MS method to detect therapeutic antibodies in animal samples using framework signature peptides

Methods to detect, characterize, and quantitate biological samples after administration of antibody conjugates, antibody-drug conjugates of Formula I, antibodies, and fragments and metabolites thereof, by immunoaffinity bead separation, chromatography, and mass spectrometry are disclosed;Ab-(L-D)&#x2003;&#x2003;I

Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry

Growing community of inventors

Belmont, CA, United States of America

Keyang Xu