Kyoto Daiichi Kagaku Co., Ltd.

Kurashiki Boseki Kabushiki Kaisha

Kexin Xu

Harumi Uenoyama

Yutaka Yamasaki

Takeshi Sakura

Hiroshi Yamamoto

Hiroko Kubo

Koji Matsuoka

Yoshio Mitsumura

Bin Xue

Hisashi Okuda

Michio Naka

Motonobu Shiomi

Keiichi Fukada

Norihito Suzuki

An acousto-optic tunable filter including: an acousto-optic crystal ; an acoustic wave driver ; and a piezoelectric transducer , is provided in front of a light source section including a plurality of light sources A, B, . . . N having different wavelength characteristics. The frequency of RF generated by the acoustic wave driver is varied in accordance with a desired wavelength. Thus, the light having the desired wavelength is incident on a converging lens as plus and minus first-order light beams, and the light having wavelengths other than the desired wavelength is incident on a converging lens as a zero-order light beam. The converging lens converges the plus and minus first-order light beams and the zero-order light beams at positions different from each other. A selector having openings located at the positions onto which the plus and first-order light beams are converged is provided in front of the converging lens . Therefore, only the light having the desired wavelength can pass through the selector and is emitted from the light source apparatus

Light source apparatus and measurement method

Method and apparatus for measuring concentration by light projection

In a non-collinear type acousto-optic tunable filter, a source light beam is made off-perpendicularly incident on a crystal body, so that the cross section of the source light beam is narrowed within the crystal body. As a result, the receiving angular aperture becomes large to increase the amount of light collected into the crystal body. Consequently, highly accurate spectrometry can be performed even if the intensity of the source light beam is low. Further, the non-diffraction part of the crystal body can be eliminated by the off-perpendicular incidence of the source light beam, so that the sufficient diffraction length of acoustic and optic waves can be obtained.

Acousto-optic tunable filter system which radiates a source light beam

In a non-collinear type acousto-optic tunable filter, the incident angle of a source light beam L.sub.1 radiated from a light source 6 onto an acoustic medium 1 is set at an equivalence incident angle for which the wavelength .lambda..sub.i of the diffracted ordinary ray L.sub.3 and the wavelength .lambda..sub.i ' of the diffracted extraordinary ray L.sub.4 become approximately identical. Further, the diffracted ordinary ray L.sub.3 and the diffracted extraordinary ray L.sub.4 of the approximately identical wavelength are superposed, and the intensity of the superposed ray is detected. Consequently, spectrometry is performed based on the superposed diffracted ray having twice the intensity and a very sharp waveform, so that accurate spectroscopy can be made possible even if the intensity of the source light beam is low.

Acousto-optic tunable filter and method of calculating its equivalence

Method of and device for positioning a living body for biological

The optical measuring apparatus of this invention for measuring a physical amount of a specific component contained in a substance to be measured by the use of measurement light which passes through the substance to be measured and the use of predetermined reference light includes: a first interfering polarizing plate for obtaining a first light interference signal by interfering the measurement light; a second interfering polarizing plate for obtaining a second light interference signal by interfering the reference light; a first photoelectric converting section for converting the first light interference signal into a first electric signal; a second photoelectric converting section for converting the second light interference signal into a second electric signal; a first phase expanding section for expanding a phase of the first electric signal; a second phase expanding section for expanding a phase of the second electric signal; a phase difference measuring section for measuring a phase difference between a phase expanded by the first phase expanding section and a phase expanded by the second phase expanding section; and a physical amount determining section for determining the physical amount of the specific component contained in the substance to be measured depending on the phase difference measured by the phase difference measuring section.

Apparatus/method for optical measuring a physical amount of a specific

A light source pa light of a plurality of wavelengths of a near infrared region, and a spectroscopic part selects a wavelength subjected to absorption by lactic acid as a measuring wavelength from measuring light of a plurality of wavelengths emitted from the light source part. A probe comes into contact with an organism measuring portion and irradiates the organism measuring portion with the measuring light of the wavelength selected by the spectroscopic part, while a photoreceiving part detects transmitted/scattered light of the measuring light incident upon the organism measuring portion. A light signal detected by the photoreceiving part is converted to absorbance in a signal processing part, so that the concentration of lactic acid is calculated by a host computer serving as an arithmetic-control part and displayed on a display part. No reagent is required, while difference between lactic acid concentrations varied with measuring portions can also be noninvasively measured.

Method of and apparatus for measuring lactic acid in organism

A method of quantitative analysis of a specific component of an object to be measured comprises steps of measuring an energy spectrum of light transmitted through or reflected from the object, dividing the energy spectrum into a plurality of wavelength domains, thereby obtaining a plurality of partial energy spectra, normalizing the plurality of partial energy spectra within each wavelength domain using an energy measured at a predetermined wavelength contained in each wavelength domain, and performing the quantative analysis by multivariate analysis using the plurality of partial energy spectra having been normalized.

Method of stabilizing spectra in spectrometry

An apparatus and method for optically measuring concentrations of components allow enhancement in measurement accuracy of concentration. The apparatus includes a cell, a light irradiator, a photodetector, and an arithmetic unit. The cell presents different optical path lengths at different locations and is to contain a sample therein. The light irradiator, which includes a variable-wavelength laser generator and a measuring system composed of convex lenses, outputs a collimated, enlarged laser beam, and makes the laser beam incident upon the cell. The photodetector comprises a multiplicity of photodetectors arranged in parallel to the surface of the cell, so that it can detect intensity of rays of transmitted light that have traveled over different optical path lengths at positions of an equal distance from the cell. The arithmetic unit, receiving a signal from the individual photodetectors, calculates concentrations of components in the sample based on optimum optical path lengths for different wavelengths and values of transmitted light at positions of the optimum optical path lengths, and further outputs calculation results.

Apparatus and method for optically measuring concentrations of components

An apparatus and method for measuring component concentrations which enables accurate measurement of concentrations of component within an object in a non-destructive, non-invasive, and bloodless procedure. The apparatus comprises a light irradiator 1 for projecting pulse laser of different wavelengths toward an object 12 by means of a variable wavelength laser generating unit 11, a photodetector 2 for performing a time resolved measurement of the quantity of transmitted light from the object which is subject to changes with lapse of time after the generation of the pulse laser, and an arithmetic unit 3 for calculating concentrations of components in the object 12 and outputting the calculation result such that the relationship between time lapse and measured quantity of light is converted into a relationship between an optical path length representing the distance of light travel within the object 12 and a change in the measured quantity of light relative to a change in unit concentration so that the optical path length and the quantity of light which is measured when the change in the quantity of light is at a peak are stored in memory for each wavelength, the quantity of light being used as a basis for the calculation.

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Kyoto, Japan

Kexin Xu