Leland Stanford Junior University

Other

Heartport, Inc.

Kevin Vincent Grimes

Hanson S Gifford, Iii

Michi E Garrison

David Mark Taylor

Wesley D Sterman

Daniel C Rosenman

Jan Komtebedde

A Adam Sharkawy

Pinaki Ray

Edward Rubenstein

Paul Laszlo Bollyky

Nadine Nagy

The present invention is an insert having a raised region that contacts an arch region of a wearer's foot, which may be selectively reinforced with a removable supplemental support. In exemplary embodiments, the insert includes a heel region adapted to receive at least a region of a heel of a wearer, and the raised region has a length situated along a width of the insert and adapted to underlie a calcaneus-midtarsal connection of a foot the wearer. The raised region is defined by a bottom semi-cylindrical surface that forms a cavity below the raised region so that an apex of the bottom semi-cylindrical surface lies above a bottom flat surface of the insert. Inside the cavity, the support is removably coupled to the cavity for selectively increasing or decreasing a rigidity of the raised region of the insert in order to apply a user-selected therapeutic pressure.

Device and method for treating heel pain

4-methylumbelliferone is useful for the treatment of autoimmune diseases, such as primary sclerosing cholangitis (PSC).

Methods of treatment using 4-methylumbelliferone and derivatives thereof

The present disclosure provides synthesized peptides containing azetidine-2-carboxylic acid (Aze), methods for detecting antibodies to peptides containing Aze, and methods for diagnosing conditions associated with misincorporation of Aze into host proteins.

Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid

A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula of the aortic occlusion catheter. In another aspect of the invention, an arterial cannula having a curved or angled distal portion. An introducer straightens the distal portion for introduction into the patient. In still another aspect of the invention, an open-mesh stabilizer is used to stabilize a discoid occluding member.

Methods and devices for occluding the ascending aorta and maintaining circulation oxygenated blood in the patient when the patient's heart is arrested

A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula or the aortic occlusion catheter. In another aspect of the invention, an arterial cannula having a curved or angled distal portion. An introducer straightens the distal portion for introduction into the patient. In still another aspect of the invention, an open-mesh stabilizer is used to stabilize a discoid occluding member.

Methods and devices for occluding the ascending aorta and maintaining circulation of oxygenated blood in the patient when the patient's heart is arrested

Growing community of inventors

Palo Alto, CA, United States of America

Kevin Vincent Grimes