Terns Pharmaceuticals, Inc.

Kevin P Quinn

Christopher T Jones

Corey Reeves

Gary W Luehr

Olivia D Teal

Jeffrey R Jasper

Provided herein are combinations comprising a glucagon-like peptide-1 receptor (GLP-1R) agonist and a thyroid hormone receptor beta (THRβ) agonist and methods comprising administering to a subject in need thereof such combinations.

Combinations of GLP-1R and THRβ agonists and methods of use thereof

The present application provides compounds that may be used as a glucagon-like peptide-1 receptors (GLP-1R) agonist, or pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions containing such compounds, or pharmaceutically acceptable salts thereof. Methods of preparing these compounds and compositions, and methods of using these compounds and compositions to treat or prevent a disease or a condition mediated by GLP-1R, are also provided.

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San Mateo, CA, United States of America

Kevin P Quinn