Bayer Healthcare LLC

Medrad, Inc.

Bayer Medical Care Inc.

Other

Bayer Pharma Aktiengesellschaft

Kevin P Cowan

Michael A Spohn

Arthur E Uber, Iii

Barry Tucker

Edward J Rhinehart

James Albert Dedig

Mark Trocki

Michael Donald McDermott

John A Haury

David M Griffiths

Michael J Swantner

David M Reilly

Alan D Hirschman

Frederick W Trombley, Iii

Christopher David Capone

Jaroslaw Wlodarczyk

Michael J Yanniello

Richard A Seman

John A Brosovich

Jared E Neff

Barry Iddon

Ralph H Schriver

Mark W Hitchins

Raymond C Hoffman

David Berry

Patrick Campbell

James R Neill

Richard Sokolov

Eric Siu

Keith Lipford

David A Mishler

Timothy Newing

Peter John Sprada

Damian Peter Francis Savio

Gerald W Callan

Mariano Mumpower

Joseph B Havrilla

Glen P Williams

William Barone

Chet B Larrow

Stanley R Lewandowski

Martin J Gibler

Vince Delbrugge

Ronald Heller

Matthew Schrauder

Matthew J Leroch

Andrew Naples

Adam Steege

Danica Gordon

Robert Dale Parks

Benjamin Thomas Krupp

Jessie Delgado

Martin J Uram

Arthur Uber

Edward P Liscio

Bruno Fazi, Jr

James Fentress

Michael McDermott

Chelsea Marsh

Brian Cain

Christopher Scutt

Dave Berry

Sridhar R Balasubramanian

Randy Lee

Roey Flor

Henry Hernaez

Ivana Kingston

Dzmitry Liushtyk

Matthew Hoiko

Robert Redmond

Andrew Osan

Herb M Grubic

Benjamin Taggart

John Francis Kalafut

George J Misic

Stephen Sams

Herbert M Grubic

Larry McCutchan

Francis J Sciulli, Jr

Anthony S McCoppin

Russell Morrison Evans, Iii

Benjamin James Cullen

Marc A Mabie

Charles Lang

Frank A Lazzaro

James E Machek

Alison Ruth Norcott

Richard Morton

Luis Castillo

Molly Bingaman

William J Nolan, Jr

Daniel Moore

Kraig J McEwen

Steven C Rygg

Mark Silvio Profaca

Bernard J Hobi

Julie Gulick

Charles J Mutschler

Abhinav Srivastava

Joseph J Fularz

A syringe for delivery of a medical liquid to a container has a body with proximal end, a frustoconical distal end, and a cylindrical sidewall extending between the proximal end and the distal end along a longitudinal axis. The syringe includes a nozzle at a distal portion of the frustoconical distal end of the syringe, the nozzle having a throughbore providing fluid communication between an interior volume of the syringe and a medical connector configured to be connected to the nozzle. The nozzle includes a plurality of longitudinal ribs formed on an inner surface of the nozzle. The syringe is designed so that the plurality of longitudinal ribs directs a flow of a medical fluid along an inner surface of the frustoconical distal end and along an interior surface of the cylindrical sidewall of the syringe under a Coandǎ effect. Syringe and connector assemblies and methods for reducing a number of bubbles formed in a medical fluid during a syringe filling procedure are also described.

Syringe fill adapter

A fluid injector system includes at least one injector for pressurizing and delivering at least one fluid from at least one fluid reservoir, at least one fluid path section providing fluid communication between a bulk fluid reservoir and a syringe connected to the at least one injector, and at least one sensor arranged along the at least one fluid path section. The at least one sensor includes an emitter configured to emit light through the at least one fluid path section, and a detector configured to receive the light emitted through the at least one fluid path section and generate an electrical signal based on at least one property of the received light. The fluid injector system may further include at least one processor programmed or configured to determine, based on the electrical signal generated by the detector, at least one of an identity of the at least one fluid present in the fluid path section, a concentration of the at least one fluid in the fluid path section, and at least one property of the fluid path section.

System and method for detecting fluid type in tubing for fluid injector apparatus

A syringe manifold for a fluid injector assembly includes a middle body member defining an upper cavity and a lower cavity, the middle body member defining at least one fluid path in an upper surface of the middle body member and at least one fluid path in a lower surface of the middle body member, the middle body member defining at least two ports extending through the middle body member, the middle body member comprising an outlet for connection of the syringe manifold to at least one fluid delivery device; a lower body member received within the lower cavity of the middle body member, the lower body member comprising at least one connector for connection of the lower body member to a syringe assembly; and an upper body member received within the upper cavity of the middle body member.

Fluid injector and patient set therefor

A system for conducting a fluid injection procedure comprises: a loading device for filling containers with fluid; an information read/write device operatively associated with the loading device and configured to: read information related to the containers stored on information storage devices associated with the containers and write information related to an injection procedure and/or a patient to the information storage devices; and a fluid injector system configured to receive the containers after filling by the loading device and inject the contents of the containers of fluid into the patient. The loading device is configured to fill the containers with fluid based on the information related to the containers read from the information storage devices. The information read/write device is configured to write information to the information storage device. The fluid injector system is configured to read the information and use this information to program the fluid injector system.

System for conducting a fluid injection procedure

A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engageable with the piston regardless of a rotational orientation of the piston relative to the plunger.

System and method for syringe plunger engagement with an injector

An injector system for delivering a medical fluid, the injector system including an injector configured to receive at least one syringe, the injector comprising at least one piston for releasably engaging and reciprocally driving a plunger or an end wall of the at least one syringe; and a syringe retaining interface comprising one or more retaining elements configured to engage at least a portion of a distal end portion of the at least one syringe to limit movement of the at least one syringe in a distal direction relative to the injector as the medical fluid is delivered from the reservoir via distal movement of the at least one piston.

Syringe retention feature for fluid injector system

A fluid container having a proximal end having an end wall, a distal end having an open-ended neck, and a sidewall extending between the proximal end and the distal end along a longitudinal axis is described. A localized crystallinity of a polymeric material of the fluid container of at least a first region of the fluid container is greater than a crystallinity of a polymeric material of the fluid container of at least a second region. Examples of fluid containers include medical fluid containers, such as medical bottles and syringes, including rolling diaphragm-type syringes, and commercial beverage containers Articles of manufacturer formed form a polymeric material and having regions with increased localized polymeric crystallinity are also described.

Fluid-container and method for controlling crystallinity in blow-molded container

A fluid mixing device for mixing a first injection fluid and a second injection fluid includes a first fluid inlet, a second fluid inlet, a mixing chamber in fluid communication with the first and second fluid inlets, and an outlet port in fluid communication with the mixing chamber. The first fluid inlet is configured to conduct the first injection fluid in a first direction and has a first redirecting surface. The second fluid inlet is configured to conduct the second injection fluid in a second direction along a different axis from the first direction and has a second redirecting surface. The mixing chamber is configured to mix the first injection fluid and the second fluid together. The mixture of the first injection fluid and the second injection fluid exits the fluid mixing device via the outlet port.

Fluid mixing device and fluid delivery tube set including same

A syringe including a proximal end, a distal end, and a cylindrical sidewall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a fluid nozzle at a distal end of the conical distal end wall; a cylindrical load bearing wall extending axially from the cylindrical sidewall past a proximal end of the conical distal end wall; and a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load bearing wall towards the fluid nozzle over at least a portion of the conical distal end wall.

Features for angiography syringe

A cassette for holding fluid path components for a fluid injector may include a body defining at least one feature for holding at least one fluid path component for the fluid injector; and a connecting member for removably connecting the body of the cassette to the fluid injector, the connecting member operatively connected to the body, wherein the connecting member comprises at least one pivotable connecting feature protruding from the body, and wherein each of the at least one pivotable connecting feature is configured for removably connecting to a corresponding connecting feature receiver on the fluid injector such that the body is pivotally movable relative to the fluid injector between a first, unlatched position and a second, latched position in which the at least one fluid path component on the body of the cassette is positioned for operative connection to a corresponding feature of the fluid injector.

Cassette for retention of fluid path components for fluid injector system

A fluid injection system and a fluid verification system for determining the operating status of the fluid injection system, for example by confirming that a fluid reservoir, containing a fluid for injection, is fully filled with fluid and has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging processing techniques, methods, and systems are also provided to determine various injection parameters and to verify the type and certain properties of fluid that is present within the fluid reservoir.

System and method for syringe fluid fill verification and image recognition of power injector system features

Syringe plunger

A plunger for use with a syringe includes a plunger body defining a central longitudinal axis and having a proximal end, a distal end, and a circumferential sidewall connecting the proximal end and the distal end. The plunger further includes at least one retaining member associated with and extending proximally from the plunger body. The at least one retaining member has a first end connected to the plunger body, a second end proximal to the first end and radially and resiliently deflectable relative to the first end, and at least one catch on the second end. A fluid injector system includes a piston having a plunger engagement mechanism configured for interacting with the at least one retaining element of the plunger to releasably engage the plunger for reciprocally driving the plunger within a barrel of the syringe.

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Allison Park, PA, United States of America

Kevin P Cowan