Achaogen, Inc.

Kevin Michael Krause

Ryan Cirz

Logan Andrews

Allison Seiko Komirenko

Ian Friedland

Daniel John Cloutier

Adrian Jubb

Provided herein are methods of treating a bacterial infection, wherein the methods comprise administering (a) ceftibuten or a pharmaceutically acceptable salt thereof, or a hydrate of the foregoing; and (b) clavulanic acid, or a pharmaceutically acceptable salt thereof. Also provided are pharmaceutical compositions, articles of manufacture, and kits comprising a) ceftibuten or a pharmaceutically acceptable salt thereof, or a hydrate of the foregoing; and (b) clavulanic acid, or a pharmaceutically acceptable salt thereof, and uses thereof.

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San Francisco, CA, United States of America

Kevin Michael Krause