Wisconsin Alumni Research Foundation

Kevin Michael Johnson

Charles Anthony Mistretta

Julia V Velikina

Thomas M Grist

Victor M Haughton

Alexey A Samsonov

Sean Fain

Matthew Robert Smith

Oliver Wieben

Jeremy W Gordon

Micah B Brown

Jon A Cappel

Noelle C Simatic

Arinne N Lyman

Tianliang Gu

A system and method for generating magnetic resonance imaging (MRI) images is provided. The MRI system is directed to perform the dynamic contrast enhanced imaging study of the subject by exciting a two-dimensional (2D) slice within a portion of a field of view (FOV) of the MRI system and acquiring imaging data from the 2D slice by sampling k-space in a pseudorandom manner using sampling trajectories extending between a center of k-space and peripheral areas of k-space. Thereafter, the 2D slice is slid to another portion of the FOV at a velocity selected to be greater a velocity of the motion of the subject and the process is repeated for each of a plurality of 2D slices to create images of the subject where artifacts induced by the motion of the subject are reflected as geometric distortions.

System and method for controlling motion effects in magnetic resonance imaging (MRI) images

A method for magnetic resonance imaging (MRI) using a radial cone k-space trajectory is provided. The radial cone k-space trajectory is defined by the application of a radial magnetic field gradient and one or more oscillating magnetic field gradients. The amplitude of the radial magnetic field gradient increases with time before decreasing with time. While the amplitude of the radial magnetic field gradient is decreasing, the one or more oscillating magnetic field gradients are applied. As a result, the radial cone k-space trajectory is one that is oriented along an axis and that extends outward from an origin along a substantially radial trajectory before extending outward from the origin while circumscribing a conical volume having a radius that increases nonlinearly with distance from the origin.

Method for magnetic resonance imaging using radial cones k-space trajectories

A system and method for simultaneously generating spectral images and spatial images of a subject using a magnetic resonance imaging (MRI) system includes acquiring MR image data using a k-space sampling trajectory. The k-space sampling trajectory is designed to spatially oversample to elicit phase differences between oversampled points. The MR image data is jointly reconstructed into spatial and spectral images by resolving spatial information from spatial encoding associated with each of the oversampled points and resolving spectral information from the phase differences between the oversampled points.

System and method for joint reconstruction of spatial and spectral imaging data

An image reconstruction method includes reconstructing a composite image of a subject using a conventional reconstruction method. The composite image employs the best information available regarding the subject of the scan and this information is used to constrain the reconstruction of a highly undersampled image frames or improve the SNR of image frames. A blurred and normalized weighting image is produced from image frame data, and this normalized weighting image is multiplied by the composite image.

Localized and highly constrained image reconstruction method

A method for magnitude constrained phase contrast magnetic resonance imaging (MRI) is provided. The method utilizes an assumption that the image magnitude is shared across a series of images reconstructed from a set of phase contrast enhanced k-space data. In this manner, one common magnitude image and a plurality of phase images are reconstructed substantially contemporaneously from the acquired image data. The method is further applicable to other phase contrast MRI methods, such as phase contract velocimetry. Moreover, simultaneous phase contrast velocimetry and chemical shift imaging, in which water and fat signal separation is achieved, is provided.

Method for magnitude constrained phase contrast magnetic resonance imaging

Mask projection views are obtained prior to the arrival of a contrast agent during a dynamic contrast enhanced MRA study. After the arrival of the contrast agent, a set of undersampled contrast enhanced projection views are obtained for each of a plurality of time frames. Corresponding mask projection views are subtracted from the contrast enhanced projection views to provide sparse contrast enhanced projection view sets. A phase contrast scan of a region of interest is performed prior to or after the arrival of the contrast agent. The phase contrast image is used as a composite image in a HYPR reconstruction of the sparse projection view sets to produce first pass contrast enhanced images. Iterative HYPR reconstructions can also be performed to remove venous information from the reconstructed images.

Contrast enhanced MRA with highly constrained backprojection reconstruction using phase contrast composite image

A series of velocity encoded MR image frames are acquired. To increase the temporal resolution of the acquired image frames radial projections are acquired and each image frame is highly undersampled. The radial projections for each velocity encoding direction are interleaved throughout the scan and a composite phase image is reconstructed from these and used to reconstruct a velocity image for each image frame in a highly constrained backprojection method.

Highly constrained reconstruction of motion encoded MR images

A device for controlled orientation of a person's cervical spine that is compatible with medical imaging machines. The device is capable of rotation about the axis of a patient's spinal column independent of, or in addition to, flexion/extension of a patient's spinal column. The device may incorporate locking mechanisms to secure rotational orientation and may include quantitative indicators of the degree of rotation.

Device to facilitate controlled rotation of the cervical spine

A phase contrast image is produced using a 3D projection reconstruction pulse sequence. A high velocity-to-noise image is produced by using a LOW VENC motion encoding gradient. Phase wrap errors caused by high velocity flow is corrected using phase information in a HIGH VENC image produced from highly undersampled data acquired during the same scan.

Growing community of inventors

Madison, WI, United States of America

Kevin Michael Johnson