Pacesetter, Inc.

The Cleveland Clinic Foundation

Kevin L Morgan

Gene A Bornzin

Sheldon Williams

John R Helland

Michael Xiaoxuan Yang

Annapurna Karicherla

Andrew W McGarvey

Yougandh Chitre

Joseph J Florio

Anne Margaret Pianca

Wenbo Hou

Phong D Doan

Eric Falkenberg

Stuart Rosenberg

Steven Roger Conger

Christopher R Jenney

Anna Barlow

Xiaoyi Min

David J Vachon

Yong D Zhao

Scott Salys

Kerwyn Schimke

Jnyan Patel

Jeffery D Snell

Nils Holmström

Shahram Moaddeb

Buehl E Truex

J Christopher Moulder

Martin Cholette

Virote Indravudh

Anne M Shelchuk

Greg Kampa

Russell Klehn

Christopher J Fleck

Benedict L Gomperz

Janice Barstad

Dion F Davis

Conor Flannery

Grace Jang

Todor N Mazgalev

Chris Parrillo

Matt Phillips

Luz Padilla

Wendy K Wolsleger

A chamber or vasculature of a heart may be accessed via the pericardial space of the heart. Initially, the pericardial space may be accessed via a transmyocardial approach or a subxiphoid approach. A lead or other implantable apparatus may thus be routed into the pericardial space, through myocardial tissue and into the chamber or vasculature. The lead or other apparatus may be used to sense activity in or provide therapy to the heart.

Cardiac access methods and apparatus

Implementations described and claimed herein provide controlled access into the intra-pericardial space. In one implementation, a medical device comprises an outer sheath, an inner sheath, and a nose shaft. The outer sheath comprises a proximal end, a distal end, and a lumen extending between the proximal end and the distal end. The inner sheath extends through the lumen of the outer sheath and comprises a distal portion adapted to pierce the pericardial sac. The nose shaft is adapted to displace relative to a distal edge of the distal portion of the inner sheath. Displacing the distal portion of the inner sheath relative to the outer sheath until the nose shaft displaces relative to the distal edge provides controlled penetration into the intra-pericardial space.

Apparatus and method for pericardial access

The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the pericardial space to anchor the distal end portion of the lead body relative to the pericardial tissue.

Intrapericardial lead with precurved distal end portion

A delivery apparatus for accessing the pericardial space of a heart including an elongated body defining a lumen and a piercing member that extends from a distal portion of the elongated body for piercing tissue of the heart. A spring expands from a distal end of the piercing member in response to the distal end of the piercing member passing through the tissue and into the pericardial space. An electrode located on the spring in order to sense signals indicative of a distal end of the spring passing through the tissue and into the pericardial space.

Disclosed herein is an implantable medical lead. In one embodiment, the lead includes a ring electrode, a tip electrode, first and second helically wound coaxial conductor coils, and a distal coil transition. The coils extend between the proximal and distal ends of the lead. The distal coil transition is proximal to the ring electrode and near the distal end and is where the first coil transitions from being outside the second coil proximal of the distal coil transition to being inside the second coil distal of the distal coil transition.

MRI compatible lead

An implantable medical lead is disclosed herein wherein the lead employs a helical distal tip anchor having improved fixation capabilities. The implantable medical lead may include a body and a helical anchor. The body may include a distal end and a proximal end. The helical anchor may be at least one of extending and extendable from the distal end. The helical anchor may include at least one loop including first and second straight sides that intersect at a first corner.

Implantable medical lead having an anchor providing enhanced fixation

An implantable medical lead configured for improved MRI safety and heating reduction performance is disclosed herein. In one embodiment, the lead includes a tubular body having a proximal end and a distal end with a lead connector near the proximal end. In this embodiment the lead further includes a conductor extending longitudinally within the tubular body and having a proximal end that is electrically coupled to the connector and a distal end electrically coupled to a contact pin. The lead in this embodiment further includes a filter element electrically coupled to a distal end of the contact pin and a flange electrically coupled between a proximal end of the filter element and a proximal portion of an electrode. In this embodiment the flange and the proximal portion of the electrode form at least a first part of a hermetic chamber enclosing the filter element.

Implantable medical lead configured for improved MRI safety and heating reduction performance

An introducer sheath is disclosed herein. The sheath includes a tubular body. The tubular body has a proximal zone, an intermediate zone and a distal zone. The proximal zone is generally straight. The intermediate zone extends from a distal end of the proximal zone and curves in a first direction. The distal zone extends from a distal end of the intermediate zone and curves in a second direction different from the first direction.

Intrapericardial delivery tools and methods

Embodiments include electrical leads and methods of using electrical leads that may be used for delivering both cardioversion/defibrillation signals and pacing signals and sensing to target tissue. Some of these embodiments may also be used to sense and transmit electrical signals from target tissue. Some electrical lead embodiments are configured to be delivered into a patient's intrapericardial space by non-invasive methods.

Epicardial lead

A method of delivering a myocardial infarction patch to a surface of a heart is disclosed herein. In one embodiment, the method includes deploying the patch from an intra pericardial lead.

Lead deployable myocardial infarction patch

The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the percaridal space to anchor the distal end portion of the lead body relative to the pericardial tissue.

Intrapericardial lead

An attachment mechanism for creating an electrical connection between a lead and a nerve bundle is disclosed herein. The attachment mechanism includes an electrically insulative polymer material including an electrode region of the polymer material sufficiently impregnated with nanotubes to be electrically conductive.

Mechanism and method of attaching a stimulation and/or sensing electrode to a nerve

Growing community of inventors

Simi Valley, CA, United States of America

Kevin L Morgan