Other

Euthymics Bioscience, Inc.

Aton Pharma, Inc.

Louisiana State University and Agricultural & Mechanical College

Shionogi, Inc.

Dov Pharmaceutical, Inc.

Bausch Health Americas, Inc.

Kevin Halloran

Zhengming Chen

Eric J Hagen

Shyam Krishnan

Alex Comely

Michael R Halloran

Xiaoming Chen

Jean Jacob

Rex Alwyn Shipplett

Brenton William Russell

Yuri McKee

Yuri Mckee

Jean Theresa Jacob

A method of forming an ocular delivery device includes exposing a solid, shaped cellulose polymer to a solution including an active pharmaceutical ingredient (API) and a solvent capable of solubilizing the API, wherein the polymer absorbs at least a portion of the solution, including the API and solvent. The method may further include removing at least a portion of the absorbed solvent from the polymer by allowing the absorbed solvent to evaporate from the polymer or by drying the polymer. A variety of cellulose polymers may be used, including hydroxypropyl cellulose. A variety of APIs may be used, including Cyclosporine, Tobramycin and Vancomycin. Ocular delivery devices prepared by the methods may be used to treat a variety of eye disorders.

Ocular drug delivery devices

A portable step platform fits onto the hollow rungs of an extension or step ladder, providing support, security and comfort for the user performing work related tasks on the ladder. A user can easily move the device up or down on the ladder, or swing the platform out of the way when ascending or descending. Tilt adjustment is facilitated for the foot platform, to accommodate different ladder inclinations. In addition, the portable step platform is configured to allow support of a scaffold plank on the top surface.

Step attachment for ladders

An ospemifene solid dispersion for enhancing solubility and bioavailability, and methods of preparation thereof are disclosed. The solid dispersion comprises an active pharmaceutical ingredient, such as ospemifene, and a hydfophilie carrier, such as copovidone, hypromellose acetate succinate, polyvinylpyrrolidine, a polyvinylpyrrolidine/vinyl acetate co-polymer, hydroxyl propyl methylcellulose, hypromellose acetate succinate, a Eudragit&#xae; compound, hydroxypropylcellulose, a polyvinyl caprolactam-polyvinyl acetate polyethylene glycol graft co-polymer, hydroxypropyl methylcellulose phthalate, and mixtures thereof, and optionally a surfactant The ospemifene solid, dispersions can be used in methods of treating a symptom related, to menopause, such as vaginal dryness or sexual dysfunction, or in methods of treating osteoporosis.

Solid dispersions

An accessory holder for a ladder, such as an extension ladder, has a main body that attaches to the side rail of a ladder via the hollow interior of a rung, and has various adjustable hooks or arms that are configured to hold paint buckets, tools, brushes and other items for a painter or other tradesman.

Accessory attachment for ladders

The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3, 4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms.

Polymorphs of azabicyclohexane

Provided herein are compositions including diastereomers in substantially diastereomerically pure form and enantiomers in substantially enantiomerically pure form, and processes for preparing them and converting them to metyrosine.

Stereoselective synthesis of metyrosine

The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms.

A new polymorphic crystalline form of bicifadine hydrochloride, designated form B, which is more thermodynamically stable than the previously known polymorphic form of bicifadine hydrochloride, designated as form A, methods for preparing said crystalline form B and pharmaceutical compositions containing said crystalline form B.

Polymorphs of bicifadine hydrochloride

A tip tray for use in restaurants or the like which is transparent and has a pair of slide tracks or slots formed by longitudinal leg bars on the bottom. The tracks accomodate cards upon which may be printed various written messages, photos, and/or other visuals which may be viewed through the transparent tray surface.

Growing community of inventors

Somerset, NJ, United States of America

Kevin Halloran