Illumina Corporation

Illumina Cambridge Limited

Kevin Hall

Roberto Rigatti

Niall Anthony Gormley

Min-Jui Richard Shen

Vincent Peter Smith

Kay Klausing

John Moore

Avgousta Ioannou

Epameinondas Fritzilas

A method of inhibiting light-induced degradation of nucleic acids includes irradiating a portion of the nucleic acids in the presence of a detection solution comprising a polyphenolic compound. A method of detecting a nucleic acid having a fluorescent tag includes irradiating at least a portion of the nucleic acid with light of a suitable wavelength to induce a fluorescence emission and detecting the fluorescence emission. Optionally, the polyphenolic compound is gallic acid, a lower alkyl ester thereof, or mixtures thereof. A kit includes one or more nucleotides, an enzyme capable of catalyzing incorporation of the nucleotides into a nucleic acid strand and a polyphenolic compound suitable for preparing a detection solution.

Method for nucleotide detection

Growing community of inventors

Nr Saffron Walden, United Kingdom

Kevin Hall