Johns Hopkins University

Kevin Colbert

Hai-Quan Mao

Sashank Reddy

Ashish Nimgaonkar

Xiaowei Li

Russell Martin

Calvin Chang

Pankaj Jay Pasricha

Thomas Henry Jozefiak

Soumyadipta Acharya

Russell E Martin

Matthew Petney

Laura Scavo

Michael Parlato

Michelle Camacho

Pratik Patel

Ashley Polhemus

Vaishakhi Mayya

Aaron Enten

Joshua Budman

A composite material can include a gel and at least one nanostructure disposed within the gel. A method for healing a soft tissue defect can include applying a composite material to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a composite material for use in healing soft tissue defects can include providing a gel and disposing nanofibers within the gel.

Nanofiber-hydrogel composites for cell and tissue delivery

Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration

A soft tissue device can incorporate a composite material comprising a gel and at least one nanostructure disposed within the gel. A soft tissue device can further incorporate biologically active materials such as cells, tissues. A method for healing a soft tissue defect while promoting soft tissue regeneration can include applying a soft tissue device to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a soft tissue device for use in healing soft tissue defects can include providing a gel, disposing nanofibers within the gel, and a biologically active material.

The present invention provides compositions and methods for treatment of metabolic syndromes. Namely, the presently disclosed compositions and methods are provided for affecting the function of the gastrointestinal endocrine system in key regions of the gut, thereby, producing therapeutic effects on obesity, diabetes and other metabolic disorders. The compositions include components for forming luminal barriers within the gastrointestinal tract of a subject where the barrier is created in-situ via interaction of resident mucin with the mucin-interacting agent.

Composition and method for treatment of metabolic disorders

An implantable, body-driven shunt pump includes a pump body defining a fluid inlet, a fluid outlet and a fluid chamber therebetween; an inlet valve arranged in the fluid inlet, the inlet valve being a one-way valve arranged such that it is operable to allow fluid flow into the fluid chamber and to prevent fluid flow out of the fluid chamber; and an outlet valve arranged in the fluid outlet, the outlet valve being a one-way valve arranged such that it is operable to allow fluid flow out of the fluid chamber and to prevent fluid flow into the fluid chamber. The pump body includes an expandable and contractible component in a portion of the pump body that defines the fluid chamber such that the fluid chamber changes volume in response to a change in pressure of fluid in the fluid chamber.

Implantable body-driven shunt pump

The present invention is directed to a bio-fluid detector such as a hemoglobin detector having the capability of receiving, storing and transmitting health information utilizing a portable transmitter and receiver including electronic PDAs such as cell phones. Further, the present invention utilizes a non-invasive hemoglobin detector that is connected to a portable transmitter-receiver such as PDAs including, but not limited to, cell phones.

Non-invasive bio-fluid detector and portable sensor-transmitter-receiver system

Growing community of inventors

Baltimore, MD, United States of America

Kevin Colbert