Cornell University

Brown University

Kevin Bath

Barbara L Hempstead

Thomas Serre

Youssef Barhomi

Sven Eberhardt

Francis S Lee

Zachary Nado

James Kocsis

The method and system includes a plurality of test subject containers, each having a test subject therein. A plurality of video cameras is focused on the test subject containers to capture video of the behavior of each of the test subjects. The system and method also includes a storage system for storing the plurality of video from the cameras. The storage system may be local or cloud-based as is known in the art. The system further has one or more computers with a neural network configured to (a) retrieve the video from the storage system of the test subjects, (b) analyze the video to identify a plurality of observable behaviors in the test subjects, (c) annotate the video with the observed behavior classifications, and (d) store the annotated video in the storage system.

Method and system for automated behavior classification of test subjects

The invention relates to a method for determining whether a patient suffering from a condition that is susceptible to treatment with a compound that activates the brain serotonin system is susceptible or resistant to treatment with the compound. The method includes establishing whether the patient is a pre-adult, a transition age patient, or an adult and observing whether the genome of the patient contains at least one copy of a BDNF allele having a genetic alteration. The method further includes correlating the presence of the allele containing the genetic alteration with susceptibility or resistance of the patient to the treatment with the compound, wherein a pre-adult patient containing the genetic alteration is correlated as being susceptible to the treatment; a transition age patient containing the genetic alteration is correlated as being susceptible or resistant to the treatment; and an adult patient containing the genetic alteration is correlated as being resistant to the treatment.

Method for determining sensitivity or resistance to compounds that activate the brain serotonin system

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Rumford, RI, United States of America

Kevin Bath