Samsung Electronics Co., Ltd.

Samsung Life Public Welfare Foundation

Samsung Life Welfare Foundation

Keunchil Park

Youngwook Kim

Jae Young Choi

Kyung Ah Kim

Ji Min Lee

Yun Ju Jeong

Saet Byoul Lee

Ki Hyun Bae

Jin-Ho Kim

Yumi Lee

Provided are a poorly water-soluble drug delivery system, a method of preparing the same, a method of delivering a poorly water-soluble drug using the same, and a pharmaceutical composition including the same as an effective component, and more particularly, a poorly water-soluble drug delivery system aiming cancer cell specific targeting, which may variously control the kind of a cancer cell targeting material capable of specifically reacting to an antigen overexpressed in a cancer cell, thereby binding to the surface of the poorly water-soluble drug delivery system, and variously control the kind of a poorly water-soluble drug encapsulated therein depending on the kind of cancer and a therapeutic purpose, thereby being effectively applicable to a cancer treatment method.

Targeted poorly water-soluble drug delivery system, method of preparing the same, and pharmaceutical composition including the same

Provided is a method for evaluating efficacy of, or resistance to, a c-Met targeting agent including measuring a level of a PDGF protein and/or a PDGF coding gene.

PDGF as a biomarker for predicting resistance or effect of c-Met targeting drugs

A method of combination therapy for prevention and/or treatment of c-Met- and/or EGFR-induced diseases including co-administering a pharmaceutically effective amount of an EGFR antagonist and a pharmaceutically effective amount of an anti-c-Met antibody to a subject in need thereof is provided.

Method of combination therapy using an EGFR antagonist and anti-c-Met antibody

Growing community of inventors

Seoul, South Korea

Keunchil Park