Dragerwerk Aktiengesellschaft

Kerstin Wex

Thomas Wuske

Andreas Manns

A unitary collection and displacement immunoassay device for determining a toxic substance adhered to aerosols in the air is provided. The device comprises an elongated body having proximal and distal ends and encloses a space defining a collection chamber, a reaction chamber and a measurement chamber, each chamber separated by a liquid flow barrier which delays liquid transport between chambers until a vacuum source is applied to the distal end of the test device to pull liquid into the next chamber. The collection chamber contains a solution for solubilizing the toxic substance from the aerosols and a semi-permeable means for separating the solubilized toxic substance from the aerosols. The reaction chamber contains a labelled immunoreactant bound to a solid phase carrier material. The labelled reagent can be displaced by the solubilized toxic substance. The measurement chamber contains a color generating system which reacts with displaced labelled reagent to produce a colored product in proportion to the concentration of the toxic substance.

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L ubeck, Germany

Kerstin Wex