University of California

Cedars-Sinai Medical Center

Ker-Chau Li

Hsian-Rong Tseng

Leland W K Chung

Min Song

Jake Lichterman

Jiefu Chen

Jiaoti Huang

Hao Ho

Zunfu Ke

Edwin M Posadas

Yi-Tsung Lu

A method, system and computer-readable medium for assessing a disease condition of a cancer of a subject, including: receiving a blood sample from the subject; isolating a plurality of circulating tumor cells (CTCs) from the blood sample; measuring at least one of cell or cell nucleus sizes of each of the plurality of CTCs; determining a measured CTC size distribution of the plurality of CTCs based on the measuring; comparing the measured CTC size distribution to a reference CTC size distribution using a computer; and assigning the disease condition of the cancer of the subject based on the comparing.

Method of assessing disease condition of cancer

A system and method for identifying high order associations between variables in complex systems that is particularly useful where there is no correlation or weak correlation between variables due to the influence of a third variable, a ternary relationship. The ternary relationship describes how the variation in the pattern of association between a pair of variables, including its sign and strength, is mediated by a third variable. In one embodiment applied to gene expression data, the activity of pairs of correlated genes due to the activity of one or more third genes is shown.

System and method for identifying networks of ternary relationships in complex data systems

System and method for identifying networks or ternary relationships in complex data systems

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Los Angeles, CA, United States of America

Ker-Chau Li