Korea United Pharm, Inc.

Korea Advanced Institute of Science and Technology

Korea Institute of Science and Technology

Seoul National University

University-Industry Cooperation Group of Kyung Hee University

Snu Rdb Foundation

Pharmedix.co., Ltd

Keon Wook Kang

Sung Baek Jeong

Ho Young Lee

Dong Soo Lee

Kyeong Seok Lee

Dae Sik Jang

Byung Hwa Jung

Hak Cheol Kwon

Hocheol Kim

Hyun Ok Yang

Jeong Hill Park

Kwang-Seok Oh

Sung Won Kwon

Myung Sook Oh

Yoon Sik Lee

Yun Sang Lee

Dae Hong Jeong

Doheon Lee

Kyung Rok Yoon

Jin Won Yang

Gun Sung Kim

Bong Hyun Jun

Youngchul Kim

Jin Chul Paeng

Nayoun Kim

The present invention relates to a pharmaceutical composition for prevention or treatment of an allergic disease comprising a mixed extract of two or more selected from the group consisting ofroot,root, andas an active ingredient; a method for prevention or treatment of an allergic disease using the pharmaceutical composition; and a health functional food and a feed composition for improvement of an allergic disease. The composition and method of the invention can specifically inhibit the differentiation of Th2 cells and thus can be effectively used as a composition for prevention or treatment of an allergic disease.

Composition for preventing or treating allergic diseases containing mixed extract of two or more amongroot,root, andas active ingredients

Provided is a composition comprising 2,4,6-trihydroxyacetophenone (THA) as an active ingredient, and a method for preventing, alleviating or treating breast cancer using the composition by inhibiting the activity of polo-like kinase 1 (PlK1).

Pharmaceutical composition comprising THA as active ingredient for treating breast cancer

The present invention relates to a composition comprising 2,4,6-trihydroxyacetophenone (THA) as an effective ingredient for prevention or treatment of prostate cancer. THA in the present invention is a main ingredient of. The composition of the present invention effectively inhibits the growth of prostate cancer by regulating in particular the activity of polo-like kinase 1 (PLK1) and thus is expected to find useful applications in use in the prevention, alleviation, and treatment of prostate cancer in future.

Pharmaceutical composition comprising THA as effective ingredient for treatment of prostate cancer

The present invention relates to a pharmaceutical composition for preventing or treating liver fibrosis or liver cirrhosis, and more specifically, to a pharmaceutical composition for preventing or treating liver fibrosis or liver cirrhosis comprising a gold-containing agent. The pharmaceutical composition of the present invention, by comprising the gold-containing agent as an active ingredient, not only promotes M2-type transformation of macrophages but also inhibits the activation of stellate cells due to the increase of TREM-2 expression, and is thus expected to be effectively used as a pharmaceutical composition, a food composition, etc., for preventing, treating, or ameliorating liver fibrosis or liver cirrhosis. Additionally, gold-containing agents, such as auranofin, sodium aurothiomalate, and aurothioglucose, have long been used for the treatment of a different disease (rheumatoid arthritis), and thus they have an advantage in that they are less likely to cause adverse effects.

Pharmaceutical composition comprising gold-containing agent for preventing or treating liver fibrosis or liver cirrhosis

Provided is a pharmaceutical composition for preventing or treating liver fibrosis, comprising a GPR119 ligand as an active ingredient. The composition comprising the GPR119 ligand as an active ingredient significantly inhibits the expression of collagen I, transforming growth factor &#x3b2; (TGF&#x3b2;) and &#x3b1;-smooth muscle actin (&#x3b1;-SMA), thereby inhibiting HSC activation, and also significantly inhibits HSC proliferation. Therefore, the composition may be effectively applied in improvement, prevention, inhibition or treatment of liver fibrosis.

Pharmaceutical composition for preventing or treating of cirrhosis of liver comprising G protein coupled receptor 119 ligand as an active ingredient

Provided are a method for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets, and a medical imaging device for simultaneously detecting multiple targets using the method. The method includes: injecting at least one marker particle comprising Raman markers and receptors into the body of an animal, which can be a human; irradiating a laser beam onto the body of the animal; and detecting the optical signals emitted by the marker particle after the irradiation of the laser beam separately as fluorescence signals and Raman signals. The simultaneous detection of multiple targets may be performed even without scanning optical signals emitted by the marker particle individually with different optical fibers. As an examination may be performed by injecting surface-enhanced Raman marker particles, weak Raman signals may be augmented so as to obtain a more accurate diagnosis result in real time.

Method for simultaneously detecting fluorescence and raman signals for multiple fluorescence and raman signal targets, and medical imaging device for simultaneously detecting multiple targets using the method

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Seoul, South Korea

Keon Wook Kang