Sony Corporation

Sony Group Corporation

Kenzo Machida

Yoshihito Hayashi

Mari Ichimura

Noriyuki Kishii

Marcaurele Brun

Seungmin Lee

Masanobu Tanaka

Aya Murata

Kaori Kawaguchi

Shinji Omori

Takuya Kishimoto

Kazumine Ito

Naohisa Sakamoto

Marc-Aurele Brun

Aya Fuchigami

Provided is a platelet aggregation capacity analyzer including a blood coagulation system-analyzing unit that analyzes a platelet aggregation capacity based on measurement data during a coagulation process of a platelet-containing sample, and an output control unit that controls an output of results analyzed by the blood coagulation system-analyzing unit, in which the blood coagulation system-analyzing unit analyzes the platelet aggregation capacity of the platelet-containing sample based on the barb of measurement data during the coagulation process with a platelet aggregation inhibitor added to the platelet-containing sample and measurement data during the coagulation process without a platelet agonist or the platelet aggregation inhibitor added to the platelet-containing sample.

Platelet aggregation capacity analyzer, analysis method, and analysis system using complex dielectric permittivity

A measurement method of simply and quickly measuring platelet aggregation, is provided. The measurement method is a platelet aggregation analysis method, including:

Platelet aggregation analysis method, platelet aggregation analysis device, program for analyzing platelet aggregation, and platelet aggregation analysis system

To provide a system capable of evaluating a deficiency and/or a lowered function of extrinsic coagulation factors or intrinsic coagulation factors with high sensitivity by adding new procedures and apparatuses to a blood coagulation system analysis procedure, an apparatus, or the like. A blood coagulation system analysis system includes a blood coagulation system measurement apparatus that performs blood coagulation system measurement of a blood sample; and a blood coagulation system analysis apparatus including a coagulation parameter extraction unit that extracts a coagulation parameter from a measurement result by the blood coagulation system measurement apparatus, and a blood coagulation evaluation unit that evaluates a level of blood coagulation of the blood sample on the basis of the coagulation parameter, the measurement by the blood coagulation system measurement apparatus being performed under an extrinsic system acceleration condition and an intrinsic system acceleration condition.

Blood coagulation system analysis system, blood coagulation system analysis method, and blood coagulation system analysis program

Provided is a technique that allows high-accuracy electrical measurement without the influence of blood sedimentation in a case where various measurements or evaluations are performed using blood samples containing a blood cell component and a plasma component. Provided is an electrical measurement method for electrically measuring a blood sample including at least a blood cell component and a plasma component, the electrical measurement method including the step of adding a blood sedimentation inhibitor to the blood sample. Also provided is a blood sedimentation inhibitor for use in electrical measurement of a blood sample including at least a blood cell component and a plasma component, the blood sedimentation inhibitor including a non-cationic water-soluble compound and being capable of increasing specific gravity and/or viscosity of the plasma component.

Electrical measurement method, electrical measurement device, and blood condition analysis system

To provide a technology that allows for simple and highly accurate evaluation of the condition of blood. Provided is a blood condition analysis device, for analyzing the condition of a blood sample having added thereto at least one kind of drug selected from the group consisting of anticoagulation treatment cancelling agents, coagulation activators, anticoagulants, platelet activators, and antiplatelet agents, the device including a drug dosage control unit for controlling the dosage of the drug to be added to the blood sample on the basis of the hematocrit and/or hemoglobin content of the blood sample.

Blood condition analysis device, blood condition analysis system, blood condition analysis method, and blood condition analysis program for causing computer to implement the method

To an electrical characteristic measuring device that further improves the accuracy of measurement of an electrical characteristic of a blood sample. Provided is an electrical characteristic measuring device including: a measuring unit configured to measure an electrical characteristic of a blood sample; and an alert generation unit configured to issue an alert signal when an erythrocyte sedimentation rate in the blood sample exceeds a prescribed standard during measurement of the blood sample.

Electrical characteristic measuring device

A blood state analysis device () that analyzes a state of a blood sample, as used for clotting time testing, said blood sample comprising a plasma and at least one reagent, including a correction unit () configured to correct a measured blood coagulation evaluation result of the blood sample based on a relation between reference concentrations of the at least one reagent in plasma and reference blood coagulation evaluation results, the at least one reagent is an anticoagulation treatment releasing agent, a coagulation activator, an anticoagulant, a platelet activator, an antiplatelet drug, or a combination thereof and is present in the blood sample. For instance, such device () allows to correct blood clotting time results with respect to concentrations of an anti-coagulant drug present in the blood sample.

Blood state analysis device, blood state analysis system, blood state analysis method, and storage device

Provided is a microbead analysis method for a microbead. The microbead is formed in a columnar shape having a top surface and a bottom surface facing each other, as placed almost in parallel, and a side surface extending therefrom, and carries an identification pattern formed on at least one of the top surface and the bottom surface and a substance immobilized on a surface thereof having affinity to an analyte substance. The method includes detecting fluorescence emitted from the microbead surface due to interaction of the analyte substance with the substance having affinity to the analyte substance from a region including a region of the top surface and the bottom surface where there is no identification pattern formed and the side surface.

Microbead analysis method and microbead analyzer

In one example embodiment, a method fabricates microbeads, which can supply a bead set containing a various types of microbeads and having distinct populations of the respective types of microbeads. In one example embodiment, the method includes forming a hydrophilic layer made of a hydrophilic organic material on a substrate. In one example embodiment, the method includes laminating on the hydrophilic layer a thin film capable of being peeled off in the form of microbeads. In one example embodiment, the method includes forming the thin film in a given configuration by photolithography. In one example embodiment, the method includes solid-phasing a given substance on the post-formed thin films. In one example embodiment, the method includes peeling off the post-formed thin films, which have been solid-phased with the substance, from the substrate along with at least a part of the hydrophilic layer to obtain microbeads.

Method for fabricating microbeads and microbeads

A microbead automatic recognition method includes the steps of: acquiring an image of a circular surface of a cylindrical microbead having a recognition pattern created on the circular surface and a plurality of reference points also created on the circular surface; and acquiring information on the rear/front and/or orientation of the cylindrical microbead from the acquired image on the basis of the positions of the reference points.

Microbead automatic recognition method and microbead

The present application provides a process for the preparation of microbeads, including the steps of: patterning a thin film, which has been formed on a substrate, into microbead regions of at least one predetermined shape by photolithography; immobilizing a predetermined substance on the thus-patterned microbead regions; and stripping off, from the substrate, the thus-patterned microbead regions with the substance immobilized thereon.

Growing community of inventors

Kanagawa, Japan

Kenzo Machida