Other

The General Hospital Corporation

Providence Health & Services - Oregon

Hemcon Medical Technologies, Inc.

Providence Health System—oregon

Oregon Biomedical Engineering Institute

Latis, Inc.

Providence Health System

Sisters of Providence of Oregon

Kenton W. Gregory & Sisters of Providence

Sisters of Prividence in Oregon

Sisters of Providence

Tricol Biomedical, Inc.

Gregory, Kenton W.

Kenton W. Gregory

Kenton W Gregory

Simon J McCarthy

R Rox Anderson

Ralph De La Torre

William P Wiesmann

Todd D Campbell

William David Block

Arjun Kalyanpur

Lauryn L Baranowski

Staci Ann McAdams

Steven Dell

Benjamin Margolis

Grant Blackwell

Seanna Vine

Robert J Ziebol

Christopher H Porter

Hal J Oien

Mark Anders Rydell

Thomas E Haw

Benjamin Charles Martin

Hanqun Shanqquan

John M Grunkemeier

Ralph De Torre

Cyndia A Sweet

Karen Marie Ahle

Elizabeth Whitney Johansen

Jason De Camp

Brooke C Basinger

Andrew D Barofsky

Jian Xin Guo

Amanda Dayton

Daniel Allen Pederson

Aileen Nuguid

Jeffrey Yihyuan Lin

Heather Margaret Bryan

Paul F Bente, Iv

John Grunkemeier

Simon Mccarthy

Amanda Senrud

The invention provides a solid foam wound dressing useful for hemorrhage control and wound repair, as well as methods for making such a wound dressing.

Chitosan foam medical devices and methods

Embodiments herein comprise a hemostatic composition comprising a plurality of liquid expandable articles capable of expanding upon contact with a liquid. A suitable composition comprises a plurality of liquid-expandable articles that may be mechanically uncoupled from one another and therefore may be capable of moving independently from one another. The plurality of liquid-expandable articles may comprise a compressed material capable of a high-degree of expansion upon liquid contact.

Hemorrhage control devices and methods

A bandage application system of the present for hemorrhage control and/or tissue repair of the gastrointestinal tract, such as the gastrointestinal tract is provided. The system comprises a bandage for hemorrhage control and/or tissue repair of the gastrointestinal tract. It also includes an apparatus for introducing the bandage into a treatment area of the gastrointestinal tract requiring hemorrhage control and/or tissue repair, and for removing the apparatus from the treatment area without displacing the bandage from being adhered to the treatment area, and without damaging the gastrointestinal tract. Furthermore, it also has a device for adhering the bandage to the treatment area.

Systems and methods for hemorrhage control and or tissue repair

Dental dressing assemblies are formed from hydrophilic polymer sponge structures, such as a densified chitosan biomaterial. The invention also contemplates systems and methods that can be used in conjunction with stents and periodontal dressings to promote hemostasis and secondary healing in free gingival graft palatal donor sites and all other oral and maxillofacial surgical sites.

Compositions, assemblies, and methods applied during or after a dental procedure to ameliorate fluid loss and/or promote healing, using a hydrophilic polymer sponge structure such as chitosan

Systems and methods provide intraluminal delivery of a bandage structure within a body lumen or hollow body organ, e.g., for treating an injured gastrointestinal tract or an esophageal hemorrhage in a non-invasive way using endoscopic visualization. The systems and methods can be sized and configured to apply a chitosan bandage structure within a body lumen or hollow body organ, to take advantage of the mucoadhesive, antimicrobial, hemostatic, and potential accelerated wound healing properties of the chitosan material.

Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ

This invention is directed to advanced hemorrhage control wound dressings, and methods of using and producing same. The subject wound dressing is constructed from a non-mammalian material for control of severe 5 bleeding. The wound dressing for controlling severe bleeding is formed of a biomaterial comprising chitosan, a hydrophilic polymer, a polyacrylic polymer or a combination thereof, The kind of severe, life-threatening bleeding contemplated by this invention is typically of the type not capable of being stanched when a conventional gauze wound dressing is applied with conventional 10 pressure to the subject wound. The wound dressing being capable of substantially stanching the flow of the severe life-threatening bleeding from the wound by adhering to the wound site, to seal the wound, to accelerate blood clot formation at the wound site, to reinforce clot formation at the wound site and prevent bleed out from the wound site, and to substantially prohibit the flow of 15 blood out of the wound site.

Wound dressing and method for controlling severe, life-threatening bleeding

Dental dressing assemblies are formed from hydrophilic polymer sponge structures, such as a densified chitosan biomaterial.

A chitosan biomaterial is frozen in aqueous solution to form a frozen chitosan structure from which water is removed by a prescribed freeze-drying process to form a sponge-like chitosan structure having a thickness and a density. The sponge-like chitosan structure is compressed by application of heat and pressure to reduce the thickness and increase the density of the sponge-like chitosan structure to form a densified chitosan structure. The densified chitosan structure is further preconditioned by heating the densified chitosan structure according to prescribed conditions to form a wound dressing. The wound dressing possesses an adhesion strength and resistance to dissolution in high blood flow bleeding situations.

Wound dressings, apparatus, and methods for controlling severe, life-threatening bleeding

This invention is directed to advanced hemorrhage control wound dressings, and methods of using a producing same. The subject wound dressing is constructed from a non-mammalian material for control of severe bleeding. The wound dressing is formed of a biomaterial comprising chitosan for controlling severe bleeding. The kind of severe, life-threatening bleeding contemplated by this invention is typically of the type not capable of being stanched when a conventional gauze wound dressing is applied with conventional pressure to the subject wound. The wound dressing being capable of substantially stanching the flow of the severe life-threatening bleeding from the wound by adhering to the wound site, to seal the wound, to accelerate blood clot formation at the wound site, to reinforce clot information at the wound site and prevent bleed out from the wound site, and to substantially prohibit the flow of blood out of the wound site.

This invention is directed to advanced hemorrhage control wound dressings, and methods of using and producing same. The subject wound dressing is constructed from a non-mammalian material for control of severe bleeding. The wound dressing for controlling severe bleeding is formed of a biomaterial comprising chitosan, a hydrophilic polymer, a polyacrylic polymer or a combination thereof. The kind of severe, life-threatening bleeding contemplated by this invention is typically of the type not capable of being stanched when a conventional gauze wound dressing is applied with conventional pressure to the subject wound. The wound dressing being capable of substantially stanching the flow of the severe life-threatening bleeding from the wound by adhering to the wound site, to seal the wound, to accelerate blood clot formation at the wound site, to reinforce clot formation at the wound site and prevent bleed out from the wound site, and to substantially prohibit the flow of blood out of the wound site.

It is a general object of the invention to provide a method of effecting repair or replacement or supporting a section of a body tissue using tropoelastin, preferably crosslinked tropoelastin and specifically to provide a tropoelastin biomaterial suitable for use as a stent, for example, a vascular stent, or as conduit replacement, as an artery, vein or a ureter replacement. The tropoelastin biomaterial itself can also be used as a stent or conduit covering or coating or lining.

Method for using tropoelastin and for producing tropoelastin biomaterials

An automated energy irradiator guidance system is disclosed which reduces the potential for human error and improves the consistency and repeatability of tissue welding techniques. The system includes a mapper, a patternizer, an energy director and can additionally include an energy regulator. An interface is included, allowing pattern creation, selection and editing by a user. The system further provides control of energy irradiator parameters for use in tissue welding.

Automated tissue welding system and method

The invention is directed to a method including the steps of providing at least one layer of unlaminated elastin or unlaminated elastin-based materials or unlaminated tropoelastin materials. Then, the unlaminated elastin or unlaminated elastin-based materials or unlaminated tropoelastin materials is subjected to heating and pressing steps. The pressing step of the present invention is preferably conducted in the presence of steam. The laminated elastin or laminated elastin-based materials or laminated tropoelastin materials preferably comprises a multi-layer composite material. Typically, the step of adhering with an adhesive material the laminated elastin or laminated elastin-based materials or laminated tropoelastin materials is employed in order to achieve a water-tight engagement with the tissue substrate. A biogradable cyanacrylate glue is generally used in order to achieve quick and easy way to secure the patch in place and provide watertight fusion instantly. Preferably, the adhesive material comprises an alkoxy alkyl cyanoacrylate material.

Methods for producing elastin, and tropoelastin products for repairing and or replacing tissue

A myocardial revascularization device has a catheter suitable for use in a myocardial revascularization procedure, the catheter including an elongate body having a proximal end and a distal end, and tissue-ablating means housed at least partially within the catheter and capable of effectuating tissue ablation adjacent the distal end of the catheter. The device further has an optical reflectance fiber housed within the catheter and coupled to an optical reflectance system. The device is operative to transmit a reflectance signal in the optical reflectance fiber, the reflectance signal including either short optical pulses or low-coherence light. The optical reflectance system is operative to gauge tissue ablation, measure a thickness of tissue adjacent the catheter, and/or determine a position of the distal end relative to adjacent tissue using either of optical time-domain reflectance or optical coherence interferometry.

Myocardial revascularization-optical reflectance catheter and method

Growing community of inventors

Portland, OR, United States of America

Kenton W Gregory