Kaneka Corporation

Kaneka Americas Holding, Inc.

Kento Kanaya

Akihisa Kanda

Takahiro Ueda

Shiro Kitamura

Koichi Kinoshita

Yoshikazu Kawai

Masao Sato

Takahiro Okubo

Masaru Hirano

Ken-ichiro Morio

Yasuyuki Suzuki

Takafumi Yamaguchi

Yosuke Aoki

Hiroko Okatsu

Kazuya Yokoe

A production system includes an information processing device that carries out the processes of: (i) generating one or more production condition candidates each of which is a candidate for a production condition under which the product is produced; (ii) determining, using a prediction model, a prediction of a production result of a case in which the product is produced under each of the one or more production condition candidates; and (iii) generates, by evaluating a result of the prediction based on a predetermined evaluation standard, an evaluation of each of the one or more production condition candidates. The information processing device repeats the process (ii) while changing between the one or more production condition candidates, and determines a production condition candidate, the evaluation of which in the process (iii) satisfies a predetermined standard, to be the production condition under which the product is produced.

Production system, information processing method, and production method

A process for producing reduced coenzyme Qincludes removing moisture from an aqueous suspension including a reduced coenzyme Q-containing microbial cell or a disrupted cell thereof such that a de-moisturized substance is obtained and in contact with an oxidizing atmosphere, and that an oxidized coenzyme Qis produced in an amount of 50 mass % or more relative to a total amount of the oxidized and reduced coenzymes Q, and reducing the oxidized coenzyme Qoutside a microbial cell such that a reduced coenzyme Qis recovered.

[object Object]

The objective of the present invention is to provide to a method for easily producing high-performance porous cellulose beads having high mechanical strength. Also, the objective of the present invention is to provide an adsorbent produced from the high-performance porous cellulose beads. According to the present invention, high-performance porous cellulose beads can be easily produced from porous cellulose beads, and an adsorbent having high strength and high adsorption amount can be easily produced from the high-performance porous cellulose beads.

Production method for porous cellulose beads, and adsorbent employing same

The present invention provides an efficient method for industrially producing a naturally-derived carotenoid composition with a large amount of a carotenoid such as astaxanthin from a culture of a yeast of the genuswithout requiring any special extraction equipment and any complicated refinement process and without any need for organic solvents harmful to humans. Provided is a method for producing a carotenoid composition, including the steps of washing a carotenoid-containing yeast of the genuswith an organic solvent (A) at 30&#xb0; C. or lower, and extracting a carotenoid from the washed yeast with an organic solvent (B) at 10&#xb0; C. to 70&#xb0; C.

Method for producing carotenoid composition

Provided is a production method of a lipophilic bioactive substance, which includes mixing an aqueous suspension of a microbial cell containing the lipophilic bioactive substance or a microbial cell homogenate thereof and an organic solvent in the presence of a particular surfactant, and extracting the lipophilic bioactive substance into the organic solvent phase. This production method enables extraction without using special dehydrating, drying facility, and without causing a decrease in the yield due to degraded separability between solvent and fungus body component, as well as efficient industrial production.

Method for manufacturing a fat-soluble bioactive substance

The present invention aims to provide a production method capable of industrially and producing coenzyme Qparticles having a high content and superior powder flowability characteristics by simple facility and convenient operations. The present invention provides a method of producing coenzyme Qparticles, including mixing coenzyme Qand a poor solvent by stirring at a temperature not less than the melting point of coenzyme Q, dispersing coenzyme Qinto the form of oil droplets, and cooling them to a solidification temperature of coenzyme Qor below while stirring the dispersion to give solid particles, wherein the poor solvent is an aqueous solution comprising an organic solvent and/or a surfactant having an HLB of 6 or above. According to the production method of the present invention, coenzyme Qparticles markedly superior in powder characteristics, and having, for example, a powder flowability index of not less than 80 can be obtained.

Method for producing coenzyme Q10 particle

A method for production of fine microcapsules which encapsulate a hydrophilic bioactive substance at a high content and can be used in wide range of applications such as foods and medical drugs, which method enabling efficient industrial production, is provided. A method for production of S/O type microcapsules including the steps of: (1) emulsifying and dispersing a mixture of a solid fat and an aqueous solution containing a hydrophilic bioactive substance at a temperature of at least the melting point of the solid fat to obtain a W/O emulsion; (2) removing moisture in the W/O emulsion at a temperature of at least the melting point and lower than the boiling point of the solid fat to obtain an S/O suspension; (3) adding the S/O suspension into an aqueous phase containing at least one selected from a surfactant (B), a thickening agent and a hydrophilic organic solvent, and permitting liquid droplet dispersion at a temperature of at least the melting point and lower than the boiling point of the solid fat to obtain an S/O/W emulsion; and (4) cooling the S/O/W emulsion to lower than the melting point of the solid fat to harden the solid fat, and further removing the moisture at a temperature lower than the melting point of the solid fat.

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Takasago, Japan

Kento Kanaya