Exostat Medical, Inc.

Optical Sensors, Inc.

Kent R Winger

Victor E Kimball

Irvin T Pierskalla

Brandon W Reynolds

A physiologic sensor for measuring the partial pressure of carbon dioxide is provided. The sensor includes a generally C-shaped in cross-section sensor cover, the sensor cover defining an opening on an underside thereof; a membrane body housed within the opening, the membrane comprising an amorphous fluoroplastic, the membrane including a first end and a second end and defines a chamber therewithin; a sensor body for coupling the membrane to the sensor cover; two or more electrodes positioned within the membrane chamber; and a substantially electrolyte-free liquid contained within the membrane chamber and in contact with the two or more electrodes.

Tissue perfusion sensor and placement device

Carbon dioxide sensor

The invention provides a device for contacting a surface of a patient's body to determine a physiologic parameter in a measurement region of a tissue of the patient. The device typically comprises a sensor responsive to the physiologic parameter and a probe housing the sensor. The probe is constructed to allow the sensor to be secured at a sensing site adjacent to the measurement region, without disturbing the blood flow within the measurement region of the tissue. The device may also include a means for reducing interference in the sensing area. Preferably, the device further comprises an indicating means operably connected to the sensor for indicating an analyte quantity and/or concentration associated with the physiologic parameter.

Detection of a physiologic parameter with a probe

The invention provides a device for contacting a surface of a tissue within a patient's body to determine a physiologic parameter of the patient. The device typically comprises a sensor responsive to the physiologic parameter and a probe housing the sensor. The probe is constructed to allow the sensor to be secured at a sensing area adjacent to a surface of a patient's tissue, without need for an adhesive and without disturbing the blood flow within the measurement region of the tissue. The device may also include a means for reducing interference in the sensing area. Preferably, the device further comprises an indicating means operably connected to the sensor for indicating an analyte quantity and/or concentration associated with the physiologic parameter. The invention also provides a method for determining a physiologic parameter of a patient.

Noninvasive detection of a physiologic parameter within a body tissue of a patient

The invention relates to a cartridge for packaging an analyte-containing fluid calibrant. The cartridge is formed from a container having an opening sealed by a sealing member. A septum divides the container into a calibrant compartment and an outer compartment. A probe is provided comprising an analyte-detecting portion and a connecting portion that allows for operative connection to a device for quantitating or determining the concentration of the analyte. The probe may extend sealingly through the septum such that the analyte-detecting portion is located in the calibrant compartment and the connecting portion is located in the outer compartment. The construction of the cartridge provides ease and reduces the likelihood of error in calibrating the probe. The invention also relates to a method of manufacturing the cartridge and a method for calibrating a device for analyte concentration determination and quantitation using the inventive cartridge.

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Prior Lake, MN, United States of America

Kent R Winger