Microdose Therapeutx, Inc.

Kent D Mosier

Jan Olesen

Henri M Akouka

Steen G Lassen

Mark Knudsen

Craig Oakum

Brian Brandt-Madsen

Morten E Andersen

The disclosure describes an inhaler having a dosing chamber in which medicament is aerosolized with a vibrator piezoelectric transducer. A spacer is provided between a face of the transducer and a wall of the dosing chamber.

Inhalation device

The present disclosure provides an inhaler having a vibration element for aerosolizing medicament contained in a blister pack, wherein individual blister packs are positioned within the housing to be simultaneously engaged with the flow channel and the vibration element. The flow channel includes a blister pack clamping surface that engages the blister pack near the top of the crown and allows the blister three rotational degrees of freedom. The advantages of this arrangement include improved consistency and higher airspeed of the synthetic jet, as well as other advantages.

Method and device for clamping a blister within a dry powder inhaler

The present disclosure provides an inhaler having a vibration element for aerosolizing medicament contained in a blister pack, wherein a plurality of individual blister packs are arranged in a rotary cassette that fits within a housing, and wherein the individual blister packs are dragged up into a clamping position between the vibration element and a piercing element. The motion of the blister pack is controlled by a rotary disk within the housing which further coordinates the movement of the piercing and vibrating elements for the piercing and deaggregation, respectively, of the individual blister packs.

Rotary cassette system for dry powder inhaler

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Princeton, NJ, United States of America

Kent D Mosier