Medtronic Minimed, Inc.

Kenneth W Cooper

Rajiv Shah

Anirban Roy

John Joseph Mastrototaro

Bradley Chi Liang

Raghavendhar Gautham

Rebecca K Gottlieb

Gopikrishnan Soundararajan

Barry Keenan

Ying Luo

Ratnakar Vejella

David Choy

Randal C Schulhauser

Keith Nogueira

Mohsen Askarinya

Katherine T Wolfe

Larry Earl Tyler

Charles R Gordon

Brian T Kannard

Richard S Yoon

Lu Wang

Kris R Holtzclaw

Helen Lee

David Y Choy

Eunjoo Jin

Ratnaker Vejella

Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.

Determination and application of glucose sensor reliability indicator and/or metric

Disclosed are methods, apparatuses, etc. for glucose sensor signal reliability analysis.

Glucose sensor signal reliability analysis

The subject matter disclosed herein relates to systems, methods and/or devices for calibrating sensor data to be used in estimating a blood glucose concentration. A relationship between sensor signal values and reference readings may be used to estimate a relationship between sensor signal values and measurements of blood glucose concentration.

System and/or method for glucose sensor calibration

Embodiments of the invention provide analyte sensors having nanostructured electrodes as well as methods for making and using such sensors. In certain embodiments of the invention, the sensor includes a carbon nanotube electrode and a analyte limiting membrane that modulates the ability of a analyte to contact the carbon nanotube electrode.

Analyte sensors having nanostructured electrodes and methods for making and using them

According to an embodiment of the invention, a method of determining hydration of a sensor having a plurality of electrodes is disclosed. In particular embodiments, the method couples a sensor electronics device to the sensor and measures the open circuit potential between at least two of the plurality of electrodes. Then, the open circuit potential measurement is compared to a predetermined value. In some embodiments, the plurality of electrodes includes a working electrode, a reference electrode, and a counter electrode. In still further embodiments, the open circuit potential between the working electrode and the reference electrode is measured. In other embodiments, the open circuit potential between the working electrode and the counter electrode is measured. In still other embodiments, the open circuit potential between the counter electrode and the reference electrode is measured.

System and method for determining the point of hydration and proper time to apply potential to a glucose sensor

The invention disclosed herein provides methods and materials for observing the state of a sensor, for example those used by diabetic patients to monitor blood glucose levels. Typically a voltage such as a voltage pulse is applied to the sensor in order to solicit a current response from which for example, factors such as impedance values can be derived. Such values can then be used as indicators of a sensor's state, for example the state of sensor hydration, sensor noise, sensor offset, sensor drift or the like.

Methods and systems for observing sensor parameters

A method and program prevents a user from bypassing a limit placed on a specified operating life of a sensor by disconnecting and reconnecting the sensor. The present invention checks a characteristic of the sensor to see if the sensor is used prior to the connection of the sensor, and rejects the sensor if the sensor is determined to have been used before. The process of checking the characteristic of the sensor involves performing an Electrochemical Impedance Spectroscopy (EIS) procedure and calculating an impedance value. The impedance value can be compared to various threshold values for a variety of purposes including the determination of age, condition, hydration, and stabilization of the sensor.

Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy

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Valencia, CA, United States of America

Kenneth W Cooper