Helmholtz-Zentrum Fur Infektionsforschung Gmbh

Helmholtz-Zentrum Fuer Infektionsforschung Gmbh

Kenneth Timmis

Peter Golyshin

Manuel Ferrer

Wolf-Rainer Abraham

Julia Sabirova

Heinrich Lunsdorf

Olga Golyshina

Heinrich Lünsdorf

Julia Lab Of Industrial Microbiology And Biocatalysis Sabirova

The present invention is in the field of biosynthesis of polyhydroxyalkanoates (PHA). The invention relates to a genetically engineered microorganism having at least one gene involved in the metabolism, preferably in the production, of polyhydroxyalkanoates (PHA). This microorganism is useful in commercial production of polyhydroxyalkanoates. The present invention further relates to a method for the production of polyhydroxyalkanoates (PHA).

Extracellular polyhydroxyalkanoates produced by genetically engineered microorganisms

The present invention relates to enzymes having catalytic activity at a pH below 5.0. The present invention provides hydrolyzing enzymes obtainable from archaeobacteria, in detail to hydrolytic enzymes obtainable from the archaeobacterium. In general, the present invention provides enzymes which are active and stable at acidic pH values, especially at pH values from 1 to 4, especially in the range of pH 2 to 3, obtainable from, especially to an esterase, glycosidases and a DNA ligase. In addition to stability and activity at low pH values, the enzymes according to the present invention are all dependent on Fefor their catalytic activity.

Acidophilic enzymes

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Wolfenbuttel, Germany

Kenneth Timmis