Eli Lilly and Company

Kenneth S Hirsch

Charles David Jones

Harold M Taylor

James E Audia

David E Lawhorn

Leland O Weigel

Loretta A McQuaid

Eriks V Krumkalns

Mark Alan Winter

C David Jones

Richard P Pioch

Donald G Saunders

This invention relates to hexa- and octaahydrobenzo�f!quinolin-3-ones, pharmaceutical formulations containing those compounds and methods of their use as steroid 5.alpha.-reductase inhibitors.

Benzo �F! quinolinones

This invention relates to hexa- and octahydrobenzo[f]quinolin-3-ones, pharmaceutical formulations containing those compounds and methods of their use as steroid 5.alpha.-reductase inhibitors.

Benzo(F)quinolinones

This invention relates to hexa- and octahydrobenzo [f]quinolin-3-ones, pharmaceutical formulations containing those compounds and methods of their use as steroid 5.alpha.-reductase inhibitors.

Benzo[F]quinolinones

The invention relates to 1,2,3,4,5,6-hexahydrobenzo[f]quinolin-3-ones, pharmaceutical formulations containing those compounds, and their use as steroid 5.alpha.-reductase inhibitors.

Hexahydrobenzo[f]quinolinones

This invention provides azole derivatives, their pharmaceutical formulations, and their use in methods of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals.

Aromatase inhibitors from azoles

Aromatase inhibitors

This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain amine derivatives.

Method of inhibiting aromatase

Certain 5-phenyl-5H-indeno[1,2-d]pyrimidines, their pharmaceutical formulations, and their use in methods for inhibiting aromatase and treating or preventing estrogen-dependent diseases.

Indenopyrimidine aromatase inhibitors

This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain amine derivatives. Pharmaceutical formulations of the compounds are also provided.

This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals which comprises administering certain imidazole derivatives.

This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain pyrazine derivatives. Pharmaceutical formulations of the pyrazine derivatives are also provided.

This invention provides for a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain pyrimidine derivatives. Pharmaceutical formulations of the pyrimidine derivatives are also provided.

This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain pyridine derivatives.

This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain azole derivatives.

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New Palestine, IN, United States of America

Kenneth S Hirsch