Cellstat Technologies, Inc.

Spatika Technologies Inc.

Kd Group

Kenneth R Wada

Peter J Dehlinger

Patricia J Malin

Murthy Ivaturi

David Arthur Blau

Thomas Mallory Sherlock

Robert M Studholme

Christopher J Kepner

John Meadows

Fred Stengel

A schema server receives from an application server vendor ID, solutions ID, and version fields extracted from a universally unique identifier (UUID) of a node and defining a protocol agnostic metadata schema application descriptor sheet identifier (PAMS ADS ID). The schema server retrieves from the memory a protocol agnostic metadata schema application descriptor sheet (PAMS ADS) that contains a list of property-type pairs and corresponds to the PAMS ADS ID, and sends the PAMS ADS to a host services gateway such that the host services gateway, using the PAMS ADS, establishes communications with the node and exposes an interface of the node as a web application programmer's interface (API).

Dynamically rendering an application programming interface for internet of things applications

A data transport system includes nodes configured to communicate with local devices via independent native protocols and to store a metadata schema that defines a data interface for process variables. The data transport system includes a computing system programmed to communicate with an application and the nodes using a media independent messaging service that is layered over respective communication protocols associated with the application and the nodes. The computing system receives, from the nodes, metadata corresponding to the data interface and dynamically render a web application programming interface (API) that allows users of the application to access the process variables.

Dynamic data transport between enterprise and business computing systems

High-throughput screening method and apparatus arm described. The method includes placing cells on a substrate defining a plurality of discrete microwells, at a well density of greater than about 100/cm, with the number of cells in each well being less than about 1000, and where the cells in each well have been exposed to a selected agent. The change in conductance in each well is determined by applying a low-voltage, AC signal across a pair of electrodes placed in that well, and synchronously measuring the conductance across the electrodes, to monitor the level of growth or metabolic activity of cells contained in each well. Also disclosed is an apparatus for carrying out the screening method.

High throughout screening method and apparatus

High-throughput screening method and apparatus are described. The method includes placing cells on a substrate defining a plurality of discrete microwells, at a well density of greater than about 100/cm , with the number of cells in each well being less than about 1000, and where the cells in each well have been exposed to a selected agent. The change in conductance in each well is determined by applying a low-voltage, AC signal across a pair of electrodes paced in that well, and synchronously measuring the conductance across the electrodes, to monitor the level of growth or metabolic activity of cells contained in each well. Also disclosed is an apparatus for carrying out the screening method.

High throughput screening method and apparatus

High-throughout screening method and apparatus are described. The method includes placing cells on a substrate defining a plurality of discrete microwells, at a well density of greater than about 100/cm,, with the number of sells in each well being less that about 1000, and where the cells in each well have been exposed to a selected agent. The change in conductance in each well is determined by applying a low-voltage, AC signal across a pair of electrodes placed in that well, and synchronously measuring the conductance across the electrodes, to monitor the level of growth or metabolic activity of cells contained in each well. Also disclosed is an apparatus for carrying out the screening method.

High-throughput screening method and apparatus

Computer-controlled method and apparatus for automatic melt index testing, including a housing with a base carrying a heater block having a bore therein for receiving a metal cartridge. A cartridge carousel is rotatably carried on the base, and carries a plurality of such cartridges, each cartridge having a plug at the bottom end thereof with a orifice through the plug, and each cartridge having a bore therein for receiving a sample of a test substance and for receiving a piston on top of the pellets. A lift arm grasps the cartridges, one at a time, and places each cartridge into the heater block, under the control of a microcomputer, by both lifting and rotating the transfer arm. The transfer arm includes a solenoid-operated grip for grasping the cartridges. The test unit carries a lift mechanism with a weight mounted atop a tamping rod, and an optical sensor for determining the height of the weight relative to the lift machinism. The weight is lowered by the lifting mechanism until it bears down upon the pellets, and then the cartridge is heated until the test substance melts. The weight is then used to extrude the melted substance through the plug orifice until it has fallen a certain distance, which operation is automatically timed by the computer. The time is then used in determining the melt index value for the substance. This operation is automatically repeated for all of the cartridges in the carousel. An automatic cut-off mechanism is used to cut off excess extrudate, and an extrudate carousel is automatically advanced to collect separate samples of the used extrudate. Optical sensors are provided to determine the motions of the components of the apparatus.

Growing community of inventors

San Jose, CA, United States of America

Kenneth R Wada