Kensey Nash Corporation

Rheologics, Inc.

Intravascular Surgical Instruments, Inc.

Visco Technologies, Inc.

Other

S.l.i.m. Tech, Ltd.

Drexel University

Bpm Devices, Inc.

Kenneth R Kensey

John E Nash

Young I Cho

William N Hogenauer

Douglas G Evans

Sangho Kim

Harold E Clupper

Sehyun Shin

Peter Randolph Hazard Stark

Sergey Kruss

Seyhun Shin

Joseph W Kaufmann

Robert Pellizzari

James J Meikle, Jr

James Meikle, Jr

Roberto O Pellizzari

Stephen Evans

Andrew R Spriegel

A blood viscosity measuring system and methods for measuring blood viscosity monitors the change in height of one of two, oppositely-moving, columns of blood from the circulating blood of a patient and, given the dimensions of a capillary tube through which the blood flows and by detecting a single blood position of the other oppositely-moving column, determines the blood viscosity over a range of shears, especially low shears. The system includes a tube set (disposable or non-disposable) that includes a pair of riser tubes, a capillary tube of predetermined dimensions that is coupled between the riser tubes (or that forms a portion of one riser tube) and a valve mechanism for controlling the circulating flow of blood from the patient into the riser tubes. A sensor monitors the movement of one of the columns of blood in one of the riser tubes and a single point detector detects a single blood position of the other column of blood and an associated microprocessor analyzes this movement and single point, along with the predetermined dimensions of the capillary tube, to determine the viscosity of the patient's circulating blood.

Dual riser/single capillary viscometer

A blood viscosity measuring system and method that monitors the rising head of a column of fluid representing a living being's blood in-vivo to determine the blood viscosity over a range of shears. The system includes a capillary tube, at least a portion of which is located within the vascular system of the being, and a riser tube, having a liquid therein coupled to the capillary tube. A sensor and associated microprocessor are provided to determine the change in the height of the liquid in the riser tube at plural points along the length of the tube from which the viscosity is calculated.

Viscosity measuring apparatus and method of use

An apparatus and method for determining the viscosity of the circulating blood of a living being over plural shear rates caused by a decreasing pressure differential by monitoring the changing weight of the blood, or the changing level of a column of blood over time. The apparatus and method utilize a riser, a capillary tube, a collector and a mass detector, such as a precision balance or a load cell, for monitoring the changing weight of a sample of fluid that flows through these components under the influence of the decreasing pressure differential; alternatively, the apparatus and method use a column level detector to monitor the changing level of the column of blood over time.

Single riser/single capillary blood viscometer using mass detection or column height detection

A method for obtaining the viscosity of the circulating blood of a living being using an adulterated blood sample and a correlation factor obtained from a circulating blood viscometer.

Method for determining the viscosity of an adulterated blood sample over plural shear rates

A blood viscosity measuring system and method that monitors the rising head of a column of fluid representing a living being's blood in-vivo to determine the blood viscosity over a range of shears. The system includes, a capillary tube, at least a portion of which is located within the vascular system of the being, and a riser tube, having a liquid therein coupled to the capillary tube. A sensor and associated microprocessor are provided to determine the change in the height of the liquid in the riser tube at plural points along the length of the tube from which the viscosity is calculated.

An apparatus and method for measuring the viscosity of Newtonian and non-Newtonian fluids over a range of shear rates, especially low shear rates, by monitoring two rising columns of fluid (Newtonian or non-Newtonian) that pass through respective capillaries having different lengths. Furthermore, a specialized column monitor is provided that uses multiple interrogation sources (e.g., lasers) and a single detector (e.g., a charge-coupled device (CCD) array) to continuously monitor both columns of fluid substantially simultaneously. In particular, the system includes a Y-connector to form two flow paths and wherein each flow path includes a tube that includes a riser tube, a capillary tube of predetermined dimensions and a valve in each for controlling the fluid flow in each path. The specialized column monitor monitors the movement of the fluid columns in each of the riser tubes and an associated microprocessor analyzes these movements, along with the predetermined dimensions of the capillary tubes and riser tubes to determine the viscosity of the fluid.

Dual riser/dual capillary viscometer for newtonian and non-newtonian fluids

A scanning rheometer is presented for the rheological property measurement of electrorheological (ER) and magnetorheological (MR) fluids using a non-linear viscoplastic model, based on the fluid height variation with respect to time. The rheometer basically includes a static (e.g., an overhead reservoir) or a dynamic source of fluid, a channel or slit whose sides form electrodes which are in contact with the flowing ER fluid, or a capillary tube exposed to a static/alternating magnetic field for flowing MR fluids, a transfer tube, either one or two riser tubes, and a column level detector for monitoring the column of fluid as it moves in one of the riser tubes. The column level detector is coupled to a processor which analyzes, among other things, column height vs. time data to determine both viscosity and yield stress. The rheometer overcomes one of the major drawbacks of the conventional rheometer: the inability to produce the yield stress of the ER, or MR, fluid in an absolute zero shear rate range. The results with this rheometer are compared with those obtained from a commercially-available rheometer which indicates excellent agreement.

Electrorheological and magnetorheological fluid scanning rheometer

An apparatus and method for determining the viscosity of a fluid over plural shear rates caused by a decreasing pressure differential by monitoring the movement of the fluid through a riser tube and a capillary tube. The movement can be monitored by detecting the changing weight of the fluid, using a precision balance or load cell, as it moves through the riser tube and capillary tube into a fluid collector; or, alternatively, the movement can be monitored by detecting the changing level of a fluid column in the riser tube using a column level detector. A processor then uses the changing weight or height data, along with the dimensions of the capillary tube and a dimension of the riser tube, to determine the viscosity of the fluid. In addition, apparatus and methods for determining fluid viscosity online and fluid mixture homogeneity online are also described.

Single riser/single capillary viscometer using mass detection or column height detection

A scanning rheometer is presented for the Theological property measurement of electrorheological (ER) and magnetorheological (MR) fluids using a non-linear viscoplastic model, based on the fluid height variation with respect to time. The rheometer basically includes a static (e.g., an overhead reservoir) or a dynamic source of fluid, a channel or slit whose sides form electrodes which are in contact with the flowing ER fluid, or a capillary tube exposed to a static/alternating magnetic field for flowing MR fluids, a transfer tube, either one or two riser tubes, and a column level detector for monitoring the column of fluid as it moves in one of the riser tubes. The column level detector is coupled to a processor which analyzes, among other things, column height vs. time data to determine both viscosity and yield stress. The rheometer overcomes one of the major drawbacks of the conventional rheometer: the inability to produce the yield stress of the ER, or MR, fluid in an absolute zero shear rate range. The results with this rheometer are compared with those obtained from a commercially-available rheometer which indicates excellent agreement.

An apparatus that allows a patient to blood let safely and automatically and which allows for the safe disposal of the withdrawn blood. The apparatus utilizes an intubator that couples to a blood vessel, a blood collector which contains a micro-biological inactivating agent and a blood conveyor which is coupled between the intubator and the blood collector for passing blood from the intubator to the blood collector.

Growing community of inventors

Hinsdale, IL, United States of America

Kenneth R Kensey