Iqvia Inc.

Quintiles Ims Incorporated

Kenneth Park

Ronald A Miller

Luther Dunlap

Dave Shell

John Muller

A method includes accessing genomic data from a first cohort and a second cohort of patients that are encrypted to comprise a probabilistic and irreversible hash of each patient's genomic sequence data; based on the probabilistic and irreversible hashes, determining one or more variants residing in a particular locale indicating where the one or more variants reside; comparing a first number of variants determined to reside in the particular locale for the first cohort of patients with a second number of variants determined to reside in the particular locale for the second cohort of patients; and in response to determining that the first number of variants determined to reside in the particular locale for the first cohort of patients and the second number of variants determined to reside in the particular locale for the second cohort of patients differ by more than a threshold value, identifying the particular locale.

System and method for genomic data analysis

A method includes accessing genomic data of from a genomic database; generating, by a processor, a first hash by probabilistically and irreversibly encrypting a first portion of the genomic data encoding the first genomic sequence, the first hash projecting the first portion into reduced dimensions such that the first portion of the genomic data encoding the first genomic sequence becomes statistically improbable to recover outside the first processor; generating, by the processor, a first cryptogram by deterministically and reversibly encrypting a second portion of the genomic data encoding the first genomic sequence; generating, by the processor, a look-up table by using at least the first cryptogram as a key and the first portion of the genomic data encoding the first genomic sequence as the value, and transmitting data encoding the first hash and the first cryptogram to one or more processors that are different from the first processor.

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New Market, MD, United States of America

Kenneth Park