Case Western Reserve University

Kent State University

Kenneth Loparo

Fred M Discenzo

Angela L Ridgel

Hassan Mohammadi-Abdar

Mark A Griswold

Dan Ma

Jeffrey L Sunshine

Nahal Geshnizjani

Example apparatus and methods employ an artificial neural network (ANN) to automatically design magnetic resonance (MR) pulse sequences. The ANN is trained using transverse magnetization signal evolutions having arbitrary initial magnetizations. The trained up ANN may then produce an array of signal evolutions associated with a pulse sequence having user selectable pulse sequence parameters that vary in degrees of freedom associated with magnetic resonance fingerprinting (MRF). Efficient and accurate approaches are provided for predicting user controllable MR pulse sequence settings including, but not limited to, acquisition period and flip angle (FA). The acquisition period and FA may be different in different sequence blocks in the pulse sequence produced by the ANN. Predicting user controllable MR pulse sequence settings for both conventional MR and MRF facilitates achieving desired signal characteristics from a signal evolution produced in response to an automatically generated pulse sequence.

Magnetic resonance fingerprinting (MRF) serial artificial neural network (ANN) sequence design

A system for use in rehabilitation of a target patient is provided. The system includes at least two bicycle devices for use by the target patient and a second operator other than the target patient. The at least two bicycle devices each include pedals. At least one of the pedals may have at least one sensor mounted thereon for monitoring operation of the first bicycle device and the target's condition. A servomotor is coupled to the pedals for providing gear-like resistance or pedal assistance for the at least two bicycle devices. A controller is programmed to electrically couple the at least two bicycle devices to each other.

Bike system for use in rehabilitation of a patient

Growing community of inventors

Cleveland, OH, United States of America

Kenneth Loparo