Boehringer Ingelheim Pharmaceuticals, Inc.

Kenneth James Koenig

Said Saim

Stephen T Horhota

David Joseph Bochniak

Disclosed is a method of small particle precipitation, retention and dispersion of a solid or semi-solid material onto or into a carrier material. In this method, solute particles are precipitated from a pressurized gaseous fluid solution or a liquid solution and effectively retained and dispersed within a carrier material. This technique can be advantageously used in pharmaceutical processing to produce a blend of solid or semi-solid material particles and carrier material, a granulation of the solid or semi-solid material particles with carrier material, carrier material partially or fully coated with the solid or semi-solid material particles, or mixtures thereof.

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New Milford, CT, United States of America

Kenneth James Koenig