Pacesetter, Inc.

Ventritex, Inc.

National Semiconductor Corporation

Kenneth J Carroll

Benjamin D Pless

Alan H Ostroff

Peter M Jacobson

Benjamin T Persson

Gene A Bornzin

Matthew G Fishler

Stephen T Archer

Michiel Pertijs

Alexander K Khairkhahan

Paul M Paspa

Eric J Varady

Gleb V Klimovitch

Saurabh Vats

Morteza Zarrabian

A leadless cardiac pacemaker is provided which can include any number of features. In one embodiment, the pacemaker can include a tip electrode, pacing electronics disposed on a p-type substrate in an electronics housing, the pacing electronics being electrically connected to the tip electrode, an energy source disposed in a cell housing, the energy source comprising a negative terminal electrically connected to the cell housing and a positive terminal electrically connected to the pacing electronics, wherein the pacing electronics are configured to drive the tip electrode negative with respect to the cell housing during a stimulation pulse. The pacemaker advantageously allows p-type pacing electronics to drive a tip electrode negative with respect to the can electrode when the can electrode is directly connected to a negative terminal of the cell. Methods of use are also provided.

Implantable leadless pacemakers

Biostimulator circuit with flying cell

Disclosed herein are implantable medical devices (IMDs) including a receiver and a battery, and methods for use therewith. The receiver includes first and second differential amplifiers, each of which monitors for a predetermined signal within a frequency range and drains power from the battery while enabled, and while not enabled drains substantially no power from the battery. To remove undesirable input offset voltages, each of the differential amplifiers, while enabled, is selectively put into an offset correction phase during which time the predetermined signal is not detectable by the differential amplifier. At any given time at least one of the first and second differential amplifiers is enabled without being in the offset correction phase so that at least one of the differential amplifiers is always monitoring for the predetermined signal. In this manner, the receiver is never blind to signals, including the predetermined signals, sent by another IMD.

Always on receiver with offset correction for implant to implant communication in an implantable medical system

The present disclosure provides systems and methods for classifying signals of interest in a cardiac rhythm management (CRM) device. A CRM device includes an intrinsic activation sensing circuit configured to pass signals falling within a first passband, a crosstalk sensing circuit configured to pass signals falling within a second passband, wherein the second passband contains higher frequencies than the first passband, and a computing device communicatively coupled to the intrinsic activation sensing circuit and the crosstalk sensing circuit, the computing device configured to classify a signal of interest as one of an intrinsic activation signal and a crosstalk signal based on whether the signal of interest is passed by the intrinsic activation sensing circuit and the crosstalk sensing circuit.

Systems and methods for classifying signals of interest in a cardiac rhythm management device

A leadless cardiac pacemaker comprises a hermetic housing, a power source disposed in the housing, at least two electrodes supported by the housing, a semiconductor temperature sensor disposed in the housing, and a controller disposed in the housing and configured to deliver energy from the power source to the electrodes to stimulate the heart based upon temperature information from the temperature sensor. In some embodiments, the sensor can be configured to sense temperature information within a predetermined range of less than 20 degrees C. The temperature sensor can be disposed in the housing but not bonded to the housing.

Temperature sensor for a leadless cardiac pacemaker

In accordance with an embodiment, apparatuses and methods are provided for coordinating operation between leadless pacemakers (LPs) located in different chambers of the heart. A method includes configuring a local LP to receive communications from a remote LP through conductive communication over first and second channels, maintaining the first channel active for at least a portion of a time when the second channel is inactive to listen for event messages from the remote LP, detecting an incoming signal at the local LP over the first channel, determining whether the incoming signal received over the first channel corresponds to an LP wakeup notice, when the incoming signal corresponds to the LP wakeup notice, activating the second channel at the local LP, and receiving an event message over the second channel from the remote LP.

System and method for low power communication between implantable devices

A leadless cardiac pacemaker comprises a housing, a plurality of electrodes coupled to an outer surface of the housing, and a pulse delivery system hermetically contained within the housing and electrically coupled to the electrode plurality, the pulse delivery system configured for sourcing energy internal to the housing, generating and delivering electrical pulses to the electrode plurality. The pacemaker further comprises an anti-unscrewing feature disposed on either a fixation device of the pacemaker or on the housing itself. The anti-unscrewing feature can be configured to prevent the fixation device from disengaging the wall of the heart.

Leadless cardiac pacemaker with anti-unscrewing feature

An integrated electrostatic discharge (ESD) protection circuitry for a signal electrode. Coupled in shunt between the signal electrode and the positive and negative power supply electrodes are opposing sets of multiple diodes coupled in series. Each set includes a diode across which is applied a nominal reverse bias voltage. These opposing reverse bias voltages are maintained at substantially constant predetermined nominal magnitudes in relation to the voltage at the signal electrode, thereby ensuring minimal leakage current via the signal electrode over the full dynamic range of the signal.

Integrated electrostatic discharge (ESD) protection circuitry for signal electrode

A circuit and method for amplifying a differential input signal over a wide dynamic range using multiple signal gains such that, over a predetermined range of values of the differential input signal, a ratio of the differential output signal to the differential input signal varies in relation to a continuous combination of the multiple signal gains.

Differential amplifier with multiple signal gains and wide dynamic range

The circuit has an output stage comprising a current source and a current sink. The circuit also has a comparison stage operable to compare a current mirrored from the current source with a current mirrored from the current sink to determine a difference therebetween. The mirrored currents may be a fraction of their corresponding output currents. Moreover, the fractions may be different from each other. A first current boost stage in the circuit is operable to provide a controlled current boost to the output stage if the difference between the compared currents crosses a threshold. The current boost may be a current sink boost or a current source boost.

Growing community of inventors

Los Altos, CA, United States of America

Kenneth J Carroll