Optiscan Biomedical Corporation

Varian Associates, Inc.

Berkeley Lights, Inc.

Visby Medical, Inc.

Click Diagnostics, Inc.

Bruker Chemical Analysis Bv

Kenneth I Li

James Roswell Braig

Jennifer H Gable

Peter Rule

Peng Zheng

Richard L Keenan

Bernhard B Sterling

Mark Wechsler

Philip C Hartstein

Gregory Loney

Alan Baldwin

Adam De La Zerda

James R Varney

Kevin M Limtao

Hamilton Roger Tang

Matthew C White

Michael J Stone

Martin J Fennell

Daniel S Goldberger

Roger C Tong

Kenneth G Witte

Julian M Cortella

Richard A King

W Dale Hall

David N Callicoat

Robert D Gaffney

Mark D Agostino

Heidi M Smith

Phillip C Hartstein

Bernard B Sterling

Mike A Munrow

John Robinson

David Klonoff

Jane J Sheill

Analytical instrument

Cartridge-based thermocyclers can include cartridges that are configured to move a fluid between distinct chambers. In some cases, the cartridge-based thermocyclers can be used for thermocycling a sample fluid comprising a deoxyribonucleic acid (DNA) target to perform polymerase chain reaction (PCR). Individual chambers can be heated, cooled, and/or compressed to mix fluid within the chamber or to propel fluid in the chamber into another chamber. The cartridges can have a laminate construction. The cartridges can be configured to enable multiplexed thermocycling and/or detection.

Cartridge-based thermocycler

Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.

Bodily fluid composition analyzer with disposable cassette

A fluid handling module that is removably engageable with a bodily fluid analyzer is provided. The module may comprise a fluid handling element, and a fluid component separator that is accessible via the fluid handling element and configured to separate at least one component of a bodily fluid transported to the fluid component separator. The fluid handling element may have at least one control element interface.

Fluid handling cassette

A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.

Analyte monitoring systems and methods

A fluid handling module is configured for removable engagement with a reusable main fluid handling instrument. The module includes a module housing and a first fluid passageway extending from the module housing. The first fluid passageway has a patient end remote from the housing. The first fluid passageway is configured to provide fluid communication with a bodily fluid in a patient. A fluid component separator is in fluid communication with the first fluid passageway. The fluid component separator is configured to separate at least one component from a portion of the bodily fluid drawn from the patient. A spectroscopic sample cell is configured to hold at least a portion of the first component.

Fluid handling cassette having a spectroscopic sample cell

Growing community of inventors

Piedmont, CA, United States of America

Kenneth I Li