University of Illinois

Northwestern University

Kenneth E Schwieter

Jeffrey S Moore

Michael Christopher Jewett

Kevin Jerome Schwarz

Joongoo Lee

Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

Growing community of inventors

Champaign, IL, United States of America

Kenneth E Schwieter