Medtronic, Inc.

Kenneth E Cobian

Michael Jay Ebert

Mark T Stewart

Mark T Marshall

Allan H Jevne

James E Upton

Richard Dean Ries

Richard L Molacek

James R Svensk

James R Keogh

Joseph F Lessar

Peter J Pohndorf

Paul C Slaikeu

Zhongping C Yang

David W Mayer

Daniel Charles Haeg

Peter B McIntyre

Phong D Doan

Genevieve L Gallagher

Tico Blumenthal

Peter M Seiler

James L Schuld

Genevieve Louise Eichenberg Gallager

A therapeutic agent reservoir comprises a reservoir body comprising a polymer and a therapeutic agent mixed within the polymer, and an outer coating enclosing the reservoir body, wherein at least a portion of the outer coating comprises a rate-controlling membrane configured to provide a predetermined release rate of the therapeutic agent through the rate-controlling membrane.

Therapeutic agent reservoir delivery system

An implantable component including a feedthrough assembly and a method for forming the feedthrough assembly wherein a coating forming a fluid barrier over an insulator, an insulator-to-terminal pin interface and an insulator-to-ferrule interface is incorporated.

Implantable device feedthrough assembly

Method of manufacturing an implantable device feedthrough assembly

This invention relates to an apparatus and a method for improving slip characteristics on the surface of a polymeric material, such as an outer surface, inner surface, or both of polymeric tubing.

Apparatus for reducing friction on polymeric surfaces

Polymeric tubing having an outer surface with a reduced coefficient of friction. The outer surface is treated by an exposure to a plasma glow discharge in the presence of an inert gas, and by deposition of a monomer during exposure to the plasma glow discharge for a time sufficient to modify the slip characteristics of the surface of the tube. The tube is preferably exposed to plasma glow discharge for a time sufficient to reduce the coefficient of friction by at least 70%. The tubing may be fabricated of silicone rubber, and the monomer deposited may be N-vinyl-2-pyrrolidone.

Plasma treated tubing

An implantable medical device has an electrode lead having an outer surface of a polymeric material which has been treated in an inert gas atmosphere by a glow discharge to deposit a monomer substance thereon to produce an outer surface lower in resistance to movement within the body tissue of a patient than untreated material.

Implantable medical device with electrode lead having improved surface

A biomedical lead conductor body formed of a coiled wire conductor that is sheathed loosely within a coiled insulative sheath of biocompatible and biostable material allowing a gap or space to be present between the exterior surface of the coiled wire conductor and the adjacent interior surface of the insulative sheath. The coiled insulative sheath is loosely fitted around the coiled wire conductor in order to compensate for defects in the coiled insulative sheath by spreading any corrosion of the wire that may take place because of the defect away from the site of a defect and along the surface of the coiled wire conductor. The lead body is incorporated into unipolar, bipolar or multi-polar biomedical leads having single filar coil windings, or multi-filar coil windings that may be redundantly electrically connected. The coiled wire conductors and coiled insulative sheaths may be parallel-wound and/or coaxially wound within the outer lead body insulative sheath. The individual coiled wire conductors may be formed of single filar wire or multi-filar wire cable and formed of single composition or composite conductive metals. The proximal and distal wire ends of the coiled wire conductors that are electrically connected in common are connected to lead connector elements and operative elements, respectively.

Coiled wire conductor insulation for biomedical lead

The present invention provides resistance to degradation from environmental stress cracking (ESC) and metal ion induced oxidation (MIO) for implantable, flexible pacing lead insulators having a body of polyether polyurethane elastomer material. A thin layer of a second polyurethane elastomer is applied as an overcoat to the lead insulator body. The second polyurethane is more resistant to ESC and MIO than the elastomer comprising the body of the insulator. Because ESC and MIO are surface phenomina, only a thin layer of the second material is required and the mechanical properties of the base material will determine the overall mechanical properties of the lead insulator.

Pacing lead insulator

An implantable lead including one or more sigmoidal or serpentine shaped conductors which are placed in one or more lumens formed in and extending along the length of the lead body. The conductor is shaped with its undulating curve lying generally in one plane. The lumen in cross section is greater in width than in height. The sigmoidal conductor extends along the length of the lead body and across the width of the lumen.

Medical electrical lead having sigmoidal conductors and non-circular

An implantable multi-lumen, multi-conductor lead for use with an implantable medical device. The completed lead is an assembly of a polymeric lead body with several coiled conductors inserted into the lead body. The lead body includes several lumens having a generally rounded-corner triangular or 'pie-shaped' cross-section. The conductors do not fill the lumens, and only contact the inner walls of the lumens at discrete points, rather than for extended sections of or all of the circumference of the conductors. Preferably the coils are sized so that they fit loosely within the lumens.

Medical electrical lead

A cardiac pacing lead has a plurality of individually insulated conductors arranged as a multifilar coil. The lead includes a connector assembly and a ring electrode assembly, each of which are optimized for use in conjunction with conductors arranged in the form of a multifilar coil. The connector assembly takes the form of an in-line connector having a plurality of linearly arranged connecting surfaces, each coupled to one of the conductors in the multifilar coil. The ring electrode assembly is constructed such that it displays the same outer diameter as the pacing lead. In both assemblies, conductors are coupled by means of welds, rather than by crimping or swaging.

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St. Anthony, MN, United States of America

Kenneth E Cobian