Glaxosmithkline Intellectual Property Development Limited

Glaxo Group Limited

Glaxogrouplimited

Kenneth David Down

Julie Nicole Hamblin

Joelle Le

Nigel James Parr

Timothy John Ritchie

Ian Robert Baldwin

Simon Gaines

Paul Faulder

Christian Alan Paul Smethurst

Christopher James Lunniss

Juliet Kay Simpson

Nicholas Paul Barton

Andrew Sharpe

Vipulkumar Kantibhai Patel

Anthony William James Cooper

Edward Paul Cannons

William Henry Miller

Paul Spencer Jones

Kevin James Doyle

Suzanne Elaine Keeling

Charlotte Jane Mitchell

Niall Andrew Anderson

Graham George Adam Inglis

Sebastien Andre Campos

Gemma Victoria White

Simon Peace

Sophie Marie Bertrand

Armelle Le Gall

Matthew Campbell

Katherine Louise Jones

Yoshiaki Washio

John Edward Robinson

Andrew Baxter

Curt Dale Haffner

Zoe Alicia Henley

Eric Philippe Andre Talbot

Jonathan Andrew Taylor

Matthew Gray

Zoe Alicia Harrison

The invention relates to compounds of formula (I) which are inhibitors of kinase activity, pharmaceutical formulations containing the compounds and their uses in treating and preventing viral infections and disorders caused or exacerbated by the viral infection wherein R, R, R, R, R, R, R, W, X, Y and Z are defined herein.

Substituted pyrazolo[1,5-a]pyrimidines as PI4K inhibitors

The invention is directed to compounds of formula (I), and salts thereof. The compounds are inhibitors of kinase activity, in particular PI3-kinase activity. 

Oxepinopyrazole derivatives as inhibitors of P13-kinase activity

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

Chemical compounds

The invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity. 

Compounds

The invention is directed to certain novel compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity. 

Benzpyrazol derivatives as inhibitors of PI3 kinases

The invention is directed to certain novel compounds directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity. 

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of P13-kinase activity. 

4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases

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Stevenage, United Kingdom

Kenneth David Down