Wallac Oy

Biocontrol Systems, Inc.

Kenneth C Rundt

Matti Korpela

Timo E Oikari

Heikki K Kouru

Jarmo Nurmi

Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel.

Method and a device for treating microparticles

Magnetic enrichment method, wherein the desired biological component is collected from a solution, which component is thereafter enriched in a liquid in such a manner that by means of the micro particles attached to the magnet or attached by means of at least one magnet at least one biological component is collected in a closed reactor vessel. Thereafter at least one biological component is enriched in such a manner that the desired component is released to the solution. The reactor unit is a closed vessel, wherein the prevailing conditions are controllable. The shape and the location of the magnet unit in the reactor unit are adjusted in a preferable manner to collect the desired biological component.

Magnetic enrichment method, a reactor unit for micro particles and a magnet unit

A magnetic transfer method for sorting, collecting, transferring or dosing microparticles () or magnetic particles either in the same liquid () or from one liquid () into another () by using a magnetic field. The transfer device () comprises a magnet () placed inside a protective coating (), and the collection or dozing is accomplished by changing the magnetic field of the magnet (). The changing of the magnetic field is effected by using a ferromagnetic body, such as a plate or tube (), comprised in the transfer device, in such manner that, when micro-particles are to be collected, the magnet is partially or completely outside the ferromagnetic body and, when the particles are to be released or dozed, the magnet is partially or completely inside or behind the ferromagnetic body.

Magnetic transfer method, a device for transferring microparticles and a reactor unit

Method for scintillation counting and a scintillation counter with

Apparatus and a method for measuring the activity of radioactive samples

In a liquid scintillation counter the light output from a liquid scintillation sample containing radioactive isotopes of unknown activity is measured by means of a detector. A pulse height analyzer having discriminators that are combined to define pulse height windows, is connected to the detector for measuring and temporarily storing count rates for each of the windows. Moreover, there are means for determining a value for the quench level of the sample. According to the invention the number of pulse height windows is at least N+1, when the number of isotopes is N,N being .gtoreq.2. There are memory means for storing for each of said windows representations of counting intensities determined by measuring calibration samples of each isotope at different levels of quench. Moreover, there are means for extracting from said stored representations a counting intensity for each window and each isotope on the basis of said determined quench level value, and means for determining for each isotope a factor by which the extracted counting intensities are to be multiplied in order to fit the sum of the extracted counting intensities to the count rates measured for the sample in each window, each said factor being directly related to the amount of each isotope in the sample.

Liquid scintillation counter for measuring the activity of radioactive

Method to determine the degree of chemical quench and the degree of color quench in liquid scintillation samples in order to find the correct counting efficiency for the samples. Scintillation pulses produced by the liquid scintillation solution as a result of an isotopic decay or in response to radiation from an external .gamma.-radiating source, are counted in a counter comprising two photodetectors working in coincidence, means for determining the value of one quench parameter dependent on the overall level of quench in the solution, and means for determining the value of another quench parameter predominantly dependent on the level of color quench in the solution. The counting efficiency for the sample can be determined on the basis of these two quench parameters.

Method for determining counting efficiency in a liquid scintillation

The invention relates to a liquid scintillation counter comprising at least two photodetectors (2,3) for viewing a scintillation solution (1) in which both real multiphoton events and single photon events take place, and producing logic pulses and amplitude pulses in correspondence to these events, the amplitude of these amplitude pulses being a function of the number of photons that reach the photodetectors (2,3) for each of said events. According to the invention there are provided means (10) for delaying the logic pulses from one of said photodetectors, means (11) for either delaying or prolonging the amplitude pulses from the same photodetector, a coincidence analyzer for analyzing by means of the undelayed logic pulses and said delayed logic pulses whether said delayed or prolonged amplitude pulses are coincident within a predetermined coincidence resolving time with the undelayed or prolonged amplitude pulses from the other photodetector, and means for determining the number of these coincidences in a plurality of pulse amplitude intervals.

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Turku, Finland

Kenneth C Rundt