Juridical Foundation the Chemo-Sero-Therapeutic Research Institute

The Chemo-Sero-Therapeutic Research Institute

Jectas Innovators Company Limited

Km Biologics Co., Ltd.

Kenji Yokogawa

Masashi Sakaguchi

Takeshi Arakawa

Eiji Tokunaga

Takeshi Miyata

Hirotaka Uefuji

Tetsuya Harakuni

Takashi Waki

Yoko Honda

Tomomitsu Sewaki

A purpose is to provide a vaccine which can prevent porcine edema disease in farms where porcine edema disease is anticipated. Meeting this purpose is a vaccine that is a fusion protein in which Stx2eB and a polypeptide having a coiled-coil forming unit are joined or a multimer of the fusion protein, and by immunizing pigs with this vaccine, it is possible to induce potent neutralizing antibodies and to defend against the onset of porcine edema disease.

Vaccine for preventing porcine edema disease

The preset invention provides a method for immunizing chickens which comprises inoculating into growing egg a composition comprising either cell-free attenuated viruses of Marek's disease type 1 or cells infected with attenuated viruses of Marek's disease type 1 capable of producing cell-free viruses. The present invention also provides a method for immunizing chickens which comprises inoculating into growing egg a mixed vaccine comprising said composition plus another vaccine from at least one microorganisms selected from the group consisting of viruses other than virus of Marek's disease type 1, bacteria and protozoan.

In ovo vaccination of marek's disease type I virus

Growing community of inventors

Kumamoto, Japan

Kenji Yokogawa