Sagami Chemical Research Center

Tosoh F-Tech, Inc.

Central Glass Company, Limited

Other

Tosoh Corporation

F-Tech Inc.

Kenji Tokuhisa

Shoji Arai

Kazuhiko Maeda

Satoru Miyazawa

Tetsu Yamakawa

Daisuke Uraguchi

Kyoko Yamamoto

Hideyuki Mimura

Takamasa Fuchikami

Noriko Wakasa

T Iii-702 Gou Kimura-Roiyarumansyon Fuchikami

Noriko; Wakasa

Provided is a reaction reagent for trifluoromethylation with high general versatility and good efficiency. The reaction reagent for trifluoromethylation contains an iron compound, trifluoromethyl iodide, a sulfoxide and a peroxide, and may further contain an acid. The iron compound is, for example, iron(II) sulfate, ammonium iron(II) sulfate, iron(II) tetrafluoroborate, ferrocene, bis(&#x3b7;-pentamethylcyclopentadienyl)iron or an iron powder; the sulfoxide is, for example, dimethyl sulfoxide; the peroxide is, for example, hydrogen peroxide or hydrogen peroxide-urea composite; and the acid is, for example, sulfuric acid, tetrafluoroboric acid or trifluoromethanesulfonic acid.

Reaction reagent for trifluoromethylation

Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound. Compounds so produced are useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals.

Nucleobase having perfluoroalkyl group and process for producing the same

The present invention relates to a polymerizable monomer represented by the general formula (1), wherein Ris a hydrogen atom, a halogen atom, a hydrocarbon group or a fluorine-containing alkyl group; Ris a straight-chain or branched alkyl group, a cyclic alkyl group, an aromatic group, or a substituent having at least two of these groups, the Rbeing optionally partially fluorinated; Ris a hydrogen atom, a hydrocarbon group that is optionally branched, a fluorine-containing alkyl group, or a cyclic group having an aromatic or alicyclic structure, the Roptionally containing a bond of an oxygen atom or carbonyl group; and n is an integer of 1-2.

Fluorine-containing polymerisable monomer and polymer prepared by using same

A process for producing a fluorine-containing acrylic acid ester represented by CH&#x2550;C(Rf)(COOR) characterized in that 1-bromo-1-perfluoroalkylethene represented by CH&#x2550;CBr&#x2014;Rf, or 1,2-dibromo-1-perfluoroalkylethane represented by CHCBr&#x2014;CHBr&#x2014;Rf is allowed to react with an alcohol represented by ROH in the presence of a palladium catalyst, carbon monoxide, and two or more kinds of bases. The fluorine-containing acrylic acid ester is a useful compound having wide applications in materials for pharmaceuticals and functional polymers.

Method for producing fluorine-containing acrylate

The present invention relates to a polymerizable monomer represented by the general formula (1), wherein Ris a hydrogen atom, a halogen atom, a hydrocarbon group or a fluorine-containing alkyl group; Ris a straight-chain or branched alkyl group, a cyclic alkyl group, an aromatic group, or a substituent having at least two of these groups, the Rbeing optionally partially fluorinated; Ris a hydrogen atom, a hydrocarbon group that is optionally branched, a fluorine-containing alkyl group, or a cyclic group having an aromatic or alicyclic structure, the Roptionally containing a bond of an oxygen atom or carbonyl group; and n is an integer of 1&#x2013;2.

Fluorine-containing polymerizable monomer and polymer prepared by using same

Fluorine-containing acrylate monomers

Growing community of inventors

Shunan, Japan

Kenji Tokuhisa