Nisshin Pharma Inc.

Kenji Takemoto

Hiroyuki Ikemoto

Masataka Harata

Shingo Nonaka

Hideki Kanai

Junichi Node

A method for producing an EPA alkyl ester-containing composition includes: preparing a raw material oil containing an EPA alkyl ester in an amount of from 50 to 92% by mass in the total fatty acids, in which a mass ratio of a DHA alkyl ester to the EPA alkyl ester contained in the raw material oil is 3.3% by mass or less and further a ratio of trans isomers in the EPA alkyl ester contained in the raw material oil is 2% by mass or less; bringing the raw material oil into contact with an aqueous solution containing a silver salt; recovering the aqueous solution containing the silver salt brought into contact with the raw material oil; bringing the recovered aqueous solution containing the silver salt into contact with an organic solvent; and recovering the organic solvent brought into contact with the aqueous solution containing the silver salt.

Eicosapentaenoic acid alkyl ester-containing composition and method for producing same

Provided is a method for producing a polyunsaturated fatty acid while suppressing deterioration of a silver salt solution. A method for producing a polyunsaturated fatty acid-containing composition, the method comprising: supplying a raw material solution comprising an alkyl ester of polyunsaturated fatty acid and an aqueous solution comprising a silver salt to a flow channel mixer to contact the raw material solution with the aqueous solution; and collecting the aqueous solution comprising the silver salt which has been contacted with the raw material solution, in which the supplying the aqueous solution comprising the silver salt to the flow channel mixer and the collecting the same are performed concurrently.

Method for producing polyunsaturated fatty acid-containing composition

Provided is a method for producing a polyunsaturated fatty acid while preventing deterioration of a silver salt solution. A method for producing a composition comprising a polyunsaturated fatty acid, comprising: supplying an aqueous solution comprising a silver salt into a reaction vessel to contact the aqueous solution with a raw material solution comprising an alkyl ester of the polyunsaturated fatty acid; and collecting the aqueous solution comprising the silver salt which has been contacted with the raw material solution from the reaction vessel, wherein the supply of the aqueous solution comprising the silver salt into the reaction vessel and the collection of the aqueous solution comprising the silver salt from the reaction vessel are carried out concurrently with each other.

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Fujimino, Japan

Kenji Takemoto