Sumitomo Chemical Company, Limited

Asahi Food Processing Co., Ltd.

Janiftec, Inc.

Eisai Company, Limited

Kenji Koga

Shiro Terashima

Norihiko Tanno

Yoshitaka Nadachi

Masayuki Mizuno

Kyosuke Kitoh

Masaru Matsuura

Makoto Asada

Yasuzo Uchida

Katsumi Tamoto

Masaki Sato

Nobuhiro Hirasawa

Sachiko Tadokoro

Kiyoshi Tomioka

Kohta Hatano

Makoto Karishu

Kazunobu Ogawa

Provided are: tofu-like food and soy milk containing fibrous material, each of which has good texture and flavor and enables simultaneous intake of almost all of nutritional components in soybeans, such as proteins, lipids, glucides, fibrous material, minerals, vitamin components, and isoflavone compounds. Also provided is a process for producing soy milk containing fibrous material, which comprises the steps of: (A) dissolving and dispersing dehulled soybean powdery material having a nitrogen solubility index of 75 to 90, a lipoxygenase value of 30 to 120, an n-hexanal content of 0.5 ppm to 2 ppm, and a peroxide value of 0.2 meq/kg to 3.0 meq/kg in water to obtain dispersion; (B) subjecting the dispersion to heat treatment at 120&#xb0; C. to 160&#xb0; C. for 1 to 600 seconds; and (C) after the step (B), cooling the dispersion to 100&#xb0; C. or lower and subjecting the resultant dispersion to emulsification and dispersion treatment under a pressure of 25 MPa to 200 MPa to produce soy milk containing fibrous material.

Soy milk containing fibrous material and tofu-like food, processes for production of those products, and dehulled soybean powder material

The present invention is substances comprising coupling isomerized highly unsaturated fatty acids and/or their derivatives having an activity of specifically promoting the uncoupling respiration of mitochondria (MC) and proton leak in the MC inner membrane in cells of the main tissues producing nonshivering thermogenesis (nST), skeletal muscles, white adipose tissue (WAT) and brown adipose tissue (BAT).

Substances having antiobese and visceral fat-reducing functions and utilization thereof

Process for producing DHA-containing tofu or soybean milk drink, or dry

An azacyclooctadiene compound having the formula (1) or a pharmacologically acceptable salt thereof is novel and useful as an anti-tumor agent. ##STR1## in which R1 is --CH2R, R being hydrogen, --COCH3, --OH, --NH2, --COOH or --OCOCH3, or may form --CH2--X--Y-- together with R2; R2 is hydrogen, an alkyl having 1 to 4 carbon atoms or --COR10, R10 being hydrogen, an alkyl having 1 to 4 carbon atoms, --OR11 or --NHR11, R11 being an alkyl having 1 to 4 carbon atoms, or may form --CH2--X--Y-- together with R1; R3, R4 and R5 each are hydrogen or methyl; R6 and R7 each are hydrogen or may form the direct bond to each other; R8 is hydrogen or may form the direct bond to R7; and R9 is hydrogen, --N3, --NH2, --OCH3 or .dbd.0; X being oxygen or --NZ--, Z being hydrogen, methyl, --COCH3, --CH2COOH, --CO--CH.dbd.CH2, --CO--CH.dbd.CH--CH3, --CH2C6H5, --CH2OH, --CH2OCOCH3 or --CH2--COOC(CH3)3, Y being --SC--, --CO-- or --CH2--.

Azacyclooctadiene compound and pharmaceutical use

A process for preparing racemic 4-demethoxy-7-deoxydaunomycinone which comprises methylating an optically active .alpha.-hydroxyketone to give the corresponding methylated product of either one of the formulas: ##STR1## and reacting the latter with an acid to give a racemate of the .alpha.-hydroxyketone of the formula: ##STR2## .

Preparation of optically active 4-demethoxydaunomycinone

2-(1'-hydroxy)ethyl-5,8-dimethoxy-3,4-dihydronaphthalene of the formula ##STR1## is produced by reducing 2-acetyl-5,8-dimethoxy-3,4-dihydronaphthalene of the formula, ##STR2## with a reducing agent obtained by reacting one equivalent of lithium aluminum hydride with one equivalent of an optically active N-substituted ephedrine of the formula, ##STR3## (wherein R.sub.1 is a C.sub.1 -C.sub.4 alkyl group or benzyl group, and Ph is phenyl group) and two equivalents of an N-substituted aniline of the formula, ##STR4## (wherein R.sub.2 is a C.sub.1 -C.sub.4 alkyl group or phenyl group, and Ph is phenyl group).

Process for producing dihydronaphthalene derivatives

Novel modified lithium aluminum hydride type reducing agents obtained by reacting one equivalent of lithium aluminum hydride with one equivalent of an optically active N-substituted ephedrine of the formula, ##STR1## (wherein R.sub.1 is a C.sub.1 -C.sub.4 alkyl group or benzyl group, and Ph is phenyl group) and two equivalents of an N-substituted aniline of the formula, ##STR2## (wherein R.sub.2 is C.sub.1 -C.sub.4 alkyl group or phenyl group, and Ph is phenyl group). This reducing agent is usable for reducing the organic compounds having a carbonyl group (ketone group or aldehyde group) in their structure into the corresponding alcohols. It is particularly useful as a reducing agent for asymmetrically reducing the unsymmetrical ketones to selectively produce either an alcohol in which the asymmetric carbon atom bonded to the hydroxy group is in R-configuration or an alcohol in which said asymmetric carbon atom is in S-configuration.

Modified lithium aluminum hydrides

A process for asymmetric synthesis of optically active 2-alkanoyl-1,2,3,4-tetrahydro-2-naphthol compounds of the formula: ##STR1## from L-proline or its ester and the following carboxylic acid of the formula: ##STR2## or its reactive derivative through the following intermediary compounds in order: ##STR3##

Novel process for asymmetric synthesis of optically active

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Tokyo, Japan

Kenji Koga