Other

Koyo Seiko Company, Ltd.

Kobayashi Pharmaceutical Co., Ltd.

Kenji Asano

Masamichi Shibata

Yutaka Tajima

Kenji Shitsukawa

Yasuaki Nagai

Yukiko Matsuda

It is an object of the present invention to provide immunopotentiators and immunotherapeutic formulations available at low cost and having a benign side effect profile. According to the present invention, an LAK activity enhancer containing an extract of Lentinus edodes mycelium and an LAK activity-enhancing formulation containing said enhancer are provided.

Lak activity potentiator orginating in shitake mushroom hyphae extract and lak activity potentiating preparations containing the same

There is provided a roller bearing in which contact stress between a roller and a raceway is uniformized by optimizing a configuration of a clearance between the roller and the raceway. A configuration of an outer circumferential surface (,) of a tapered roller (,) of a tapered roller bearing (,) is defined so that a clearance of Y(x)&equals;kYp(x), which results from multiplying an equation Yp(x) for uniformizing contact stress between infinite-width plate and tapered roller by a positive number k&equals;1.5-10, is formed between the raceway surface (,) and the outer circumferential surface (,) of the tapered roller (,). The tapered roller (,) relaxes concentration of contact stresses, improving the durability.

Roller bearing

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Osaka, Japan

Kenji Asano