Sysmex Corporation

Kenji Akama

Nobuyasu Hori

Shigeki Iwanaga

Masaya Okada

Eiji Kobayashi

Hiroyuki Noji

Seiichiro Tabata

Hiroya Kirimura

Toshiyuki Sato

Masaki Ishisaka

Yuki Aihara

Ayato Tagawa

Masatoshi Yanagida

Masaki Shibayama

Junko Kojima

Seigo Suzuki

Toshihiro Watanabe

Kunpeng Cai

Yoshinobu Miura

Kentaro Shirai

Masakazu Kadowaki

Kazuto Yamashita

Akshay Ganguly

Kenta Oda

Hana Kumamoto

Samiko Hosoya

Hori Nobuyasu

Disclosed is an analyte detection method, including detecting an analyte in such a state that a complex composed of the analyte in a sample of interest, a particle capable of bonding to the analyte and a trapping substance capable of bonding to the analyte is formed on a substrate, wherein the analyte is detected on the basis of an index associated with a behavior of the particle.

Analyte detection method

A blood collection device including a flow path to flow blood by capillary action capable of collecting a large amount of blood is provided. The blood collection device includes an introduction inletfor introducing the blood of the subject M, a substrateconnected to the introduction inletand including a flow pathto flow the blood by capillary action, and a cooling bodyfor cooling the flow path

Blood collection device, blood collection set, blood collection method

Disclosed is a method for obtaining information of a test substance, the method including: forming a complex by causing a capture substance to bind to a test substance in a specimen; selectively collecting at least the complex from the specimen; immobilizing the complex collected from the specimen, onto a base plate; and obtaining information regarding a structure of the test substance from the complex immobilized on the base plate.

Method for obtaining information of test substance

The present invention relates to a method for detecting an analyte in a sample, comprising the steps of: forming on each of carrier particles a complex containing a first capture substance capable of binding to an analyte, one molecule of the analyte, a second capture substance capable of binding to the analyte, and a catalyst; immobilizing a reaction product on each of the carrier particles by reacting the catalyst in the complex with a substrate; and detecting the analyte by detecting the carrier particles on each of which the reaction product is immobilized.

Method for detecting analyte

Disclosed is a method for detecting a test substance, including a first contact step of bringing the test substance, a capturing bodythat has binding properties to the test substance and is fixed to a substrate, and a capturing bodythat has binding properties to the test substance and contains a label into contact with each other in a liquid to arrange at least a part of the capturing bodyon the substrate; after the first contact step, a first dissociation step of dissociating a part of substances containing the capturing bodyfrom the substrate and releasing it into the liquid; after the first dissociation step, a second contact step of bringing the test substance, the capturing bodythat has binding properties to the test substance and is fixed to a substrate, and the capturing bodythat has binding properties to the test substance and contains a label into contact with each other in the liquid to arrange at least a part of the capturing bodyon the substrate; after the second contact step, a second dissociation step of dissociating a part of substances containing the capturing bodyfrom the substrate and releasing it into the liquid; and a detection step of comparing a label-derived signal arrangement pattern on the substrate after dissociation in the first dissociation step with a label-derived signal arrangement pattern on the substrate after dissociation in the second dissociation step and detecting signals at substantially the same position as a signal indicating the test substance.

Method for detecting test substance

Disclosed is a method for obtaining differentiated cells and/or differentiated cell products, including the steps of: introducing undifferentiated cells into a perfused organ or living tissue; subjecting the undifferentiated cells introduced to perfusion culture together with the organ or living tissue so as to allow the undifferentiated cells to differentiate, thereby obtaining differentiated cells and/or differentiated cell products; collecting a perfusion culture solution that contains the resulting differentiated cells and/or differentiated cell products; and obtaining the differentiated cells and/or differentiated cell products contained in the collected perfusion culture solution.

Method for obtaining differentiated cells and/or differentiated cell products from undifferentiated cell and a method of perfusion culture

A particle imaging apparatus comprises a flow path comprising a first flow path section, a second flow path section connected downstream of the first flow path section, and a third flow path section that is branched from the first flow path section, a particle detection unit comprising a light source and a light detector, a particle sorting unit configured to adjust a flow direction of the particle, and a particle imaging unit configured to take an image of a particle that flows in the second flow path section. The flow path is structured such that a cross-sectional area of the second flow path section is greater than a cross-sectional area of the first flow path section. The first flow path section and the second flow path section are disposed so as to be linearly aligned.

Particle imaging apparatus and particle imaging method

Disclosed is a method of collecting cells including the steps of: preparing a processed-bone comprising a bone extracted from a living body, a covering agent and first and second holes, wherein an outer surface of the bone is covered with the covering agent attached to the outer surface of the bone, and the first and second holes penetrate through the covering agent and the outer surface of the bone into the interior of the bone; introducing a liquid into the processed-bone from the first hole; and collecting a cell-containing liquid from the second hole.

Method of collecting cells

Growing community of inventors

Kobe, Japan

Kenji Akama