Sanraku-ocean Co., Ltd.

Sanraku Incorporated

Kenichi Yamamoto

Tomoyuki Ishikura

Takeo Yoshioka

Yasutaka Shimauchi

Yasuo Fukagawa

Yoshiaki Yagi

Michikatsu Sato

Yukio Tsuchiyama

Kaoru Yamada

Kouki Fujii

Yasuyuki Kato

A cyclodextrin adsorbing material composed of a water-insoluble resin substrate to which a ligand having such a size as to be included by cyclodextrin is chemically bonded via a spacer radical; a method of separating and purifying cyclodextrin from an aqueous solution containing it, which comprises bringing said aqueous solution into contact with the above adsorbing material to adsorb cyclodextrin on the adsorbing material, and subjecting the adsorbing material to a desorption treatment to recover cyclodextrin; and a method of increasing the amount of cyclodextrin yielded, which comprises carrying out a cyclodextrin-forming reaction by an enzymatic method in the presence of the above adsorbent material.

Cyclodextrin adsorbing-material

A compound represented by the following formula: ##STR1## wherein R.sub.1 represents a hydrogen atom or a hydroxyl group, R.sub.2 represents a group of the formula --CH.sub.2 NO.sub.2, --CN.fwdarw.O or ##STR2## in which A represents a group of the formula ##STR3## in which R.sub.4 represents a hydrogen atom or an alkoxycarbonyl group, R.sub.5 represents a phenyl, alkoxycarbonyl or alkanoyloxymethyl group, R.sub.6 represents an alkyl group and R.sub.7 represents a phenyl, naphthyl, pyridyl, furyl or thienyl group; and R.sub.3 represents a hydrogen atom or a substituted or unsubstituted hydrocarbon group, and a process for production thereof.

.beta.-Lactam derivatives and process for production thereof

Novel antibiotic .beta.-lactam compounds, i.e. 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives of the following formula ##STR1## wherein R.sub.1 represents a hydrogen atom, a methyl group or a hydroxyl group,

Antibiotic .beta.-lactam compounds, production thereof, and their use as

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Fujisawa, Japan

Kenichi Yamamoto