Mitsubishi Denki Kabushiki Kaisha

Olympus Corporation

Olympus Optical Company, Ltd.

Other

Olympus Corpration

Kenichi Koyama

Atsuhiro Tsuchiya

Hiroyuki Sasao

Kazuhiro Hasegawa

Yukimori Kishida

Hideaki Endo

Mitsuru Tsukima

Toshie Takeuchi

Akitsugu Kagayama

Ryuichi Hirano

Katsuyoshi Yamaguchi

Hideaki Toya

Akihiko Iwata

Hiroyuki Akita

Takashi Yoneyama

Akihiro Suzuki

Toshiyuki Kikunaga

Mitsumasa Yorita

Hiroshi Hasegawa

Toshimasa Maruyama

Toyomi Ooshige

Hiroshi Yamamoto

Shinji Sato

Kenji Kawasaki

Masahiro Arioka

Atsushi Yonetani

Mitsugu Takahashi

Masayoshi Karasawa

Hirobumi Suzuki

Akihiko Yoshikawa

Yoko Ohashi

Yuichi Yamaji

Kazuhiko Nishimiya

Kiyotsugu Kojima

Yasushi Takeuchi

Tetsuya Matsuda

Toshiyuki Yoshizawa

Yoshihiro Kawano

Nobuyuki Ito

Takao Tsurimoto

Masakazu Fukada

Takafumi Nakagawa

Hiromi Koga

Sadashi Adachi

Toshinori Kimura

Nobumoto Tohya

Atsushi Sawada

Masaru Fujiwara

Mitsugu Takahasi

Kazuhiko Terao

Harehiko Nomura

An object of the present invention is to provide a predetermined site luminescence measuring method and a predetermined site luminescence measuring apparatus, which allow for determining whether, when the luminescence from the predetermined site in live samples is measured, a photoprotein is localized at the predetermined site in the same ones as the samples. An predetermined site luminescence measuring apparatusin the present invention is comprised of: a the sampleinto which a fused fusion gene is introduced, the fusion gene being obtained by fusing a fluorescence-related gene that expresses a fluorescence protein in addition to a targeting base sequence and a luminescence-related gene; a containerfor storing the sample, a stageon which the containeris arranged; a luminescent image capturing unitwhich captures a luminescent image of the sample(the objective lensto the CCD camera, and the imaging lens); a fluorescent image capturing unitwhich captures a fluorescent image of the sample(the objective lensto shutter); and an the information communication terminal

Predetermined site luminescence measuring method, predetermined site luminescence measuring apparatus, expression amount measuring method, and measuring apparatus

A tissue culture microscope apparatus includes a culture unit that includes a chamber in which a specimen is put, and maintains the chamber at a predetermined temperature to culture the specimen; an observation unit that forms an observation image of the specimen put in the chamber; and a liquid supply unit that stores a liquid in a protrusion portion penetrating into a wall of the chamber and protruding to an inside of the chamber, matches a temperature of the liquid with the temperature of the chamber, and injects the liquid from the protrusion portion to the specimen.

Tissue culture microscope apparatus

A culture microscope apparatus has an illumination unit to apply excitation light to the specimen, a specimen observing portion to observe light generated from the specimen due to the excitation light, and a dimmer unit to dim the excitation light that has penetrated the specimen.

Culture microscope apparatus

A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that cultures the cultured cell, and a microscope used for observing the cultured cell. The culture device includes a first space that is controlled to an environment suitable for culture of the cell, and a second space that is controlled to a lower humidity condition in comparison with the first space. The microscope includes an objective optical unit including an objective lens; the objective optical unit having at least one portion located in the second space, and another portion extending into the first space through an opening formed in a partition wall that separates the first space and the second space, with a gap between the objective optical unit and the partition wall being sealed by a sealing member, and the objective lens includes a plurality of lens groups, with mutual spaces among the lens groups vented to the second space.

Culture observation apparatus

A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that forms a culture space which is controlled to be an environment suitable for culturing the cultured cell; a sample tray that holds a container housing the cultured cell and a culture medium; a microscope that serves for observing the cultured cell; a tray holding mechanism that holds the sample tray in the culture space in a detachable manner with good reproducibility; and a shifting mechanism that relatively shifts the sample tray held by the tray holding mechanism and a light axis of the microscope along a plane that is orthogonal to the light axis, wherein the sample tray has a heater used for heating the sample tray, and is electrically connectable to an energy supplying unit that supplies energy to the sample tray.

Culture observation apparatus, sample tray heat-insulating device and lid

A focus detection device which is applied to a fluorescent observation device for observing a fluorescent image to be emitted from an observation sample on the basis of an evanescent light, includes an image pickup unit which detects a contrast of the fluorescent image by imaging the fluorescent image, and a detector which detects a focus on the basis of the detection result.

Focus detection device and fluorescent observation device using the same

An observation apparatus includes a sample tray that holds a container housing a cultured cell and a culture medium and covered with a lid; an observation unit that serves for observation of the cultured cell; and a shifting unit that relatively shifts the sample tray and a light axis of the observation unit along a plane that is orthogonal to the light axis of the observation unit, wherein the sample tray includes a container holding unit that holds the container by utilizing an elastic force, and at least one of the lid and one portion of the lid is made detachable, with the container being held in the sample tray by the container holding unit.

Observation apparatus

Voltage compensating circuits are connected serially to a power system, including capacitors each having different charging voltages (in relationship of approximately 2(K=0, 1, 2, . . . ) times the smallest charging voltage value). The voltage compensating circuits convert DC voltages in the capacitors into AC voltages and output the AC voltages, respectively. The voltages of the capacitors are detected as detected values Vto VThe detected values Vto Vare used as bit signals for a reference value to check a voltage dip amount of the power system with the reference value and to convert the voltage dip amount into a binary signal. A combination is selected from the voltage compensating circuits in accordance with the binary signal so that the sum of output voltages of the selected voltage compensating circuits compensates the voltage dip of the power system.

Voltage fluctuation compensating apparatus

The problem to be solved by the present invention is to provide a microscope that prevents a dew condensation on an objective lens and allows obtaining a good microscopic image, and a method of preventing a dew condensation on an objective lens. A microscope includes an objective lens having a heaterin a cell incubatorhaving a high humidity space. The high humidity space is maintained at 90% to 100% of relative humidity and controlled to be at a predetermined gas temperature. A cultured cellin the cell incubatoris observed via the objective lens, and the heateris controlled to make the temperature of the objective lenshigher than the gas temperature of the high humidity space.

Microscope and method of preventing dew condensation on objective lens

A microscope system has a stage on which an observation sample, including an observation object and a transparent member, is to be placed. An objective lens is placed to face the observation sample placed on the stage, and a focusing unit moves at least one of the stage and the objective lens to perform a focusing operation. An autofocus unit controls a focusing driving unit by a so-called Through-the-Lens: TTL system. After autofocus is performed for the transparent member by the autofocus unit, the focusing driving unit makes at least one of the stage and the objective lens move by a predetermined constant amount.

Microscope system and microscope focus maintaining device for the same

A microscope illumination intensity measuring device has a light-receiving unit that outputs a signal representing an intensity of received light, a moving mechanism that places the light-receiving unit on an observation optical axis of the microscope as needed, a converter that converts a signal output from the light-receiving unit into light intensity information, a wavelength selection unit that sets a wavelength for light to be measured, and a display unit that displays the light intensity information.

Microscope illumination intensity measuring device

An in-vivo examination apparatus in which the examination angle can be changed while keeping an examination site in focus to carry out accurate in-vivo examination is provided. The in-vivo examination apparatus includes a stage on which a living organism is mounted, a measurement head that irradiates the living organism on the stage with light emitted from a light source and detects light returning from the living organism, and a rotation mechanism that rotates the measurement head about a fixed point on the stage.

In-vivo examination apparatus

Growing community of inventors

Tokyo, Japan

Kenichi Koyama