3d Global Biotech Inc.

National Applied Research Laboratories

Taipei Medical University

Ji Yan Biomedical Co., Ltd

Keng-Liang Ou

Kuo-Cheng Huang

Chen-Yu Liu

Hsin-Yi Tsai

Jen-Chang Yang

Chien-Chung Chen

Min-Wei Hung

Po-Nien Chen

Wen-Hong Wu

Kuo-Sheng Hung

Ching-Ching Yang

How Tseng

Yu-Hao Chan

Wei-Jen Cheng

Jeng-Kuen Tsai

Hsi-Jen Chiang

Cherng-You Ke

Chao-Chia Weng

Chih-Hua Yu

Jungshan Chang

Tung-kuo Tsai

Yung-Kang Shen

Yu-Sin Ou

Yin-Chung Huang

The present invention discloses a method for producing the alpha-calcium sulfate hemihydrate bone graft, which comprises the following steps: mixing calcium sulfate dihydrate and deionized water to produce calcium sulfate dihydrate paste; stirring and heating the calcium sulfate dihydrate paste at least 160&#xb0; C. within 100-350 psi to produce the conversion calcium sulfate hemihydrate, filtering the conversion calcium sulfate hemihydrate with high temperature to produce the filtered calcium sulfate hemihydrate, and washing the filtered calcium sulfate hemihydrate by absolute alcohol to get the alpha-calcium sulfate hemihydrate bone graft. The present invention does not use any catalyst, possesses a high purity, high mechanical strength, and good biocompatibility, facilitates bone growth and angiogenesis, requires only 31&#xb0; C., the highest temperature, during the curing process. It makes the present invention more secure in the biomedical applications.

Method for producing alpha-calcium sulfate hemihydrate bone graft

A system for online monitoring powder-based 3D printing processes and method thereof are disclosed. A uniform light source having a single wavelength provided by the system is irradiated onto the powder layer before and after applied with glue. Intensities of such reflected images are obtained and subtracted from each other in an image process procedure. A difference obtained through the subtraction is compared with an original 3D model in a computer. If any defect is found such as being larger than a threshold value, the powder-based 3D printing processes will be terminated. Therefore, the technical effects of online printing processes monitoring, time saving and printing resources saving will be achieved.

System for online monitoring powder-based 3D printing processes and method thereof

The present invention provides an ancillary additive manufacturing system for manufacturing a reconstructed model simultaneously during the oral surgery to effectively reduce the time and healthcare human resources for the oral surgery. The ancillary additive manufacturing system comprises an input device and a printing body. The printing body is connected to the input device and comprises a base, an ink-manufacturing module, an inkjet head controlling unit, and multiple inkjet heads. The ink-manufacturing module is located above the base and comprises first, second, and third ink-manufacturing units. The inkjet head controlling unit is located above the base. The inkjet heads are mounted to the inkjet head controlling unit and point toward the base and comprise a first, second, and third inkjet head. The first, second, and third inkjet head correspondingly connected to the first, second, and third ink-manufacturing units.

Ancillary additive manufacturing system

A bipolar electrosurgical instrument has a handle and an operation tool. The operation tool is mounted on a front end of the handle and has multiple holes densely formed in and spread over at least one working surface of the operation tool. With the multiple holes formed on the at least one working surface of the operation tool, tissues of a surgical site can be heated uniformly and adhesion of the surgical site is minimized. Moreover, since the multiple holes are directly formed on the at least one working surface, the multiple holes do not become shallow under long-term use and no toxic gas would be released when the operation tool is heated to high temperature. Accordingly, anti-adhesion effect of the operation tool and health of medical staffs can be assured.

Operation tool of bipolar electrosurgical instrument

The invention provides a method for promoting wound healing or tissue injury treatment in a subject in need thereof, the method comprising administering to the subject an effective amount of one or more fungal immunomodulatory protein (preferably,immunomodulatory protein).

Use of immunomodulatory protein in promotion of wound healing or treatment of tissue injury

The invention creates a support for cell culture and cell sheet detachment which has a substrate, whose surface is coated with a conjugate having a disulfide bond-containing amino acid as a spacer and a biopolymer enhancing cell attachment, migration or differentation. Unexpectedly, after being seeded on the support, the cells grow to form one or more layers of cell sheets and the cell sheets can be easily detached from the support by adding a reductant to cleave the disulfide bond. Accordingly, the invention provides a simple and non-toxic method for detachment of cell sheets.

Supports for cell culture and cell sheet detachment and methods for cell sheet detachment

The invention provides an electrospinning apparatus, which comprises one or more spinneret, a rotating collector disposed from the spinneret and configured to collect the fibers, and a sideway motion device disposed on or connected to the spinneret or the rotating collector and configured to propel or move the spinneret or the rotating collector, wherein the sideway motion device is controlled by a controlling unit for providing an angular speed (&#x3b8;) of the sideway motion with a formula: &#x3b8;=tanx/H wherein x is a parallel motion speed of the device and H is a vertical height between the spinneret and the rotating collector and wherein the angular speed (&#x3b8;) is in a range of about 1.0&#xd7;10to about 1.0 (&#xb0;/sec). Also provided is the 2-D or 3-D membranes produced therefrom and a method of using the apparatus of the invention.

Electrospinning apparatus with a sideway motion device and a method of using the same

A non-contact apparatus for a stability assessment of a dental implant is provided. The non-contact apparatus includes a triggering device and a dental implant containing a root body and an impact generating device, wherein the root body has a cavity, the impact generating device is located in the cavity, and the triggering device provides a non-contact impetus for triggering the impact generating device.

Non-contact apparatus and method for stability assessment of dental implant

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Kaohsiung, Taiwan

Keng-Liang Ou